Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7328061 | 0.86 | TP53 (0.43) | RXFP1KDM4ETP53NPC1MAPK1 | |
| SCHEMBL7319630 | 0.83 | ALDH1A1 (0.47) | RXFP1KDM4ETP53RAB9AMAPK1 | |
| SCHEMBL7324191 | 0.79 | SMN1; SMN2 (0.43) | KDM4ERAB9ANPC1MAPK1MAPT | |
| SCHEMBL7331816 | 0.78 | SNCA (0.52) | KDM4ERAB9AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL7361629 | 0.78 | ALDH1A1 (0.53) | RXFP1RAB9ANPC1MAPK1MAPT | |
| SCHEMBL7328793 | 0.76 | L3MBTL1 (0.47) | KDM4ERAB9ANPC1MAPTCES2 | |
| SCHEMBL7319642 | 0.76 | SMN1; SMN2 (0.42) | KDM4ERAB9AMAPK1MAPTCES2 | |
| SCHEMBL25377449 | 0.76 | TRPM8 (0.57) | KDM4EMAPTTRPM8ALDH1A1L3MBTL1 | |
| SCHEMBL8470246 | 0.75 | CES2 (0.45) | KDM4ETP53RAB9AMAPK1MAPT | |
| SCHEMBL4196693 | 0.75 | ALDH1A1 (0.49) | KDM4ETP53RAB9ANPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5075304-A | Nervous system disorders | NOVO NORDISK A/S (DK) | 1991-12-24 | — | — | US | disclosed |
| EP-0344943-A1 | Imidazoquinoxaline compounds and their preparation and use | NOVO NORDISK A/S (DK) | 1989-12-06 | — | — | EP | disclosed |