Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PREP | P48147 | 1/20 | 0.39 |
| ▸ | CCR4 | P51679 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7319764 | 0.85 | GAA (0.47) | GAAMEN1KMT2ADPP4SMN1; SMN2 | |
| SCHEMBL7370031 | 0.83 | GRM2 (0.36) | BCHEMEN1KMT2ADPP4HDAC1 | |
| SCHEMBL7265407 | 0.82 | DPP4 (0.53) | P2RX7GAAMEN1KMT2ADPP4 | |
| SCHEMBL7322701 | 0.80 | METAP2 (0.40) | MEN1KMT2AMAPTSIGMAR1 | |
| SCHEMBL7320276 | 0.78 | HPGD (0.45) | MEN1KMT2ASMN1; SMN2LMNAHPGD | |
| SCHEMBL7318026 | 0.77 | NPC1 (0.43) | P2RX7 | |
| SCHEMBL10585933 | 0.76 | L3MBTL1 (0.49) | DPP4HPGDHDAC1HDAC8HDAC6 | |
| SCHEMBL7321829 | 0.76 | ALDH1A1 (0.47) | GAAMEN1KMT2ALMNAHPGD | |
| SCHEMBL7316776 | 0.72 | P2RX7 (0.40) | P2RX7GAABCHEMEN1KMT2A | |
| SCHEMBL7319691 | 0.72 | MAPT (0.46) | MEN1KMT2AMAPTLMNAPREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280956-B1 | THIAZOLIDINE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1992-10-21 | — | — | EP | claimed |
| US-4857537-A | PREVENTING AMNESIA | ONO PHARMACEUTICAL CO., LTD. (JP) | 1989-08-15 | — | — | US | claimed |
| EP-0280956-A1 | Thiazolidine derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1988-09-07 | — | — | EP | claimed |