SCHEMBL731988

SCHEMBL731988

O=C1C2CC3OC3CC2C(=O)N1CC1CO1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.47
HBB P68871 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
POLB P06746 1/20 0.37
MAPT P10636 3/20 0.36
DHFR P00374 1/20 0.35
ALDH1A1 P00352 3/20 0.33
TSHR P16473 2/20 0.33
HSD17B10 Q99714 2/20 0.33
MEN1 O00255 1/20 0.33
HPGD P15428 1/20 0.33
NPY1R P25929 1/20 0.33
CASP1 P29466 1/20 0.33
NPY2R P49146 1/20 0.33
CASP7 P55210 1/20 0.33
KMT2A Q03164 1/20 0.33
CYP2C19 P33261 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14541350 0.83 TP53 (0.45) TP53HBBSMN1; SMN2POLBMAPT
SCHEMBL17983048 0.78 TP53 (0.48) TP53HBBSMN1; SMN2POLBMAPT
SCHEMBL963535 0.78 TP53 (0.48) TP53HBBSMN1; SMN2POLBMAPT
SCHEMBL14191451 0.77 KDM4E (0.30) TP53SMN1; SMN2
SCHEMBL258856 0.77 ALDH1A1 (0.36) TP53SMN1; SMN2POLBALDH1A1TSHR
SCHEMBL959563 0.77 ALDH1A1 (0.47) TP53HBBSMN1; SMN2MAPTDHFR
SCHEMBL21119007 0.74 TP53 (0.64) TP53HBBSMN1; SMN2POLBMAPT
SCHEMBL21119006 0.74 TP53 (0.64) TP53HBBSMN1; SMN2POLBMAPT
SCHEMBL962223 0.74 MAPT (0.39) MAPTALDH1A1HSD17B10CYP2C19CYP2C9
SCHEMBL961994 0.74 TP53 (0.52) TP53HBBSMN1; SMN2POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2028183-B1 NOVEL EPOXY COMPOUND AND METHOD FOR PRODUCING THE SAME SHOWA DENKO KK (JP) 2014-03-26 EP disclosed
US-8138296-B2 Epoxy compounds and process for their production SHOWA DENKO K.K. (JP) 2012-03-20 US disclosed
US-7863461-B2 Epoxy compounds and method for production of the same SHOWA DENKO K.K. (JP) 2011-01-04 US disclosed
US-20090253915-A1 NOVEL EPOXY COMPOUNDS AND METHOD FOR PRODUCTION OF THE SAME SHOWA DENKO K.K. (JP) 2009-10-08 US disclosed
EP-2029653-B1 NOVEL EPOXY COMPOUNDS AND PROCESS FOR THEIR PRODUCTION SHOWA DENKO KK (JP) 2009-09-30 EP disclosed
US-20090182110-A1 NOVEL EPOXY COMPOUNDS AND PROCESS FOR THEIR PRODUCTION SHOWA DENKO K.K. (JP) 2009-07-16 US disclosed
EP-2029653-A1 NOVEL EPOXY COMPOUNDS AND PROCESS FOR THEIR PRODUCTION Showa Denko K.K. (JP) 2009-03-04 EP disclosed
EP-2028183-A1 NOVEL EPOXY COMPOUND AND METHOD FOR PRODUCING THE SAME Showa Denko K.K. (JP) 2009-02-25 EP disclosed
WO-2007142248-A1 NOVEL EPOXY COMPOUNDS AND PROCESS FOR THEIR PRODUCTION SHOWA DENKO K.K. (JP) 2007-12-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090182110-A1 NOVEL EPOXY COMPOUNDS AND PROCESS FOR THEIR PRODUCTION ELOVL3, ACSL3, ACSL4 TP53 4596/4885HBB 2303/4885SMN1; SMN2 4751/4885
US-20090253915-A1 NOVEL EPOXY COMPOUNDS AND METHOD FOR PRODUCTION OF THE SAME PTGIS, PTGES, CYP2E1 TP53 4395/4885HBB 2949/4885SMN1; SMN2 4382/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.