Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 12/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 11/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7322626 | 1.00 | TRPA1 (0.53) | TRPA1OPRK1ADRA2BADRA2CSLC6A2 | |
| SCHEMBL5383411 | 1.00 | TRPA1 (0.53) | TRPA1OPRK1ADRA2BADRA2CSLC6A2 | |
| Methyl Carbamate SCHEMBL28108901 | 0.85 | OPRM1 (0.47) | OPRK1OPRD1OPRM1 | |
| SCHEMBL27783352 | 0.82 | OPRK1 (0.59) | TRPA1OPRK1ADRA2BADRA2CSLC6A2 | |
| SCHEMBL24305562 | 0.82 | OPRD1 (0.55) | OPRK1SLC6A2OPRD1OPRM1 | |
| SCHEMBL6318927 | 0.81 | HPGD (0.50) | TRPA1OPRK1ADRA2BADRA2CSLC6A2 | |
| SCHEMBL19385457 | 0.81 | HPGD (0.50) | TRPA1OPRK1ADRA2BADRA2CSLC6A2 | |
| SCHEMBL9915838 | 0.81 | OPRK1 (0.52) | TRPA1OPRK1ADRA2BADRA2CSLC6A2 | |
| SCHEMBL13453034 | 0.81 | OPRK1 (0.52) | TRPA1OPRK1ADRA2BADRA2CSLC6A2 | |
| SCHEMBL13453338 | 0.81 | OPRK1 (0.52) | TRPA1OPRK1ADRA2BADRA2CSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106458866-A | Aminocarbonyl carbamate compound | 爱思开生物制药株式会社 | 2017-02-22 | — | — | CN | claimed |
| US-20230218562-A1 | AMINOCARBONYLCARBAMATE COMPOUNDS | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2023-07-13 | — | — | US | disclosed |
| CN-109627186-B | Aminocarbonyl carbamate compound | 爱思开生物制药株式会社 | 2021-10-29 | — | — | CN | disclosed |
| US-20210113514-A1 | AMINOCARBONYLCARBAMATE COMPOUNDS | SK BIOPHARMACEUTICALS., LTD. | 2021-04-22 | — | — | US | disclosed |
| US-10888542-B2 | Aminocarbonylcarbamate compounds | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2021-01-12 | — | — | US | disclosed |
| US-20200046674-A1 | AMINOCARBONYLCARBAMATE COMPOUNDS | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2020-02-13 | — | — | US | disclosed |
| EP-3110792-B1 | AMINOCARBONYLCARBAMATE COMPOUNDS | SK BIOPHARMACEUTICALS CO LTD (KR) | 2019-09-04 | — | — | EP | disclosed |
| US-20190247356-A1 | Aminocarbonylcarbamate Compounds | SK BIOPHARMACEUTICALS CO., LTD. | 2019-08-15 | — | — | US | disclosed |
| US-10314808-B2 | Aminocarbonylcarbamate compounds | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2019-06-11 | — | — | US | disclosed |
| US-20180085337-A1 | AMINOCARBONYLCARBAMATE COMPOUNDS | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2018-03-29 | — | — | US | disclosed |
| CN-106458866-A | Aminocarbonyl carbamate compound | 爱思开生物制药株式会社 | 2017-02-22 | — | — | CN | disclosed |
| EP-3110792-A1 | AMINOCARBONYLCARBAMATE COMPOUNDS | SK Biopharmaceuticals Co., Ltd. (KR) | 2017-01-04 | — | — | EP | disclosed |
| US-20160303067-A1 | AMINOCARBONYLCARBAMATE COMPOUNDS | SK BIOPHARMACEUTICALS CO., LTD. | 2016-10-20 | — | — | US | disclosed |
| US-9403761-B2 | Aminocarbonylcarbamate compounds | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2016-08-02 | — | — | US | disclosed |
| WO-2015130121-A1 | AMINOCARBONYLCARBAMATE COMPOUNDS | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2015-09-03 | — | — | WO | disclosed |
| US-20150246874-A1 | AMINOCARBONYLCARBAMATE COMPOUNDS | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2015-09-03 | — | — | US | disclosed |
| CN-1027262-C | Benzazepine and benzothiazepine derivatives | E R SQUID & SONS INC (US) | 1995-01-04 | — | — | CN | disclosed |
| US-4902684-A | Benzazepine and benzothiazepine derivatives | E. R. SQUIBB & SONS, INC. (US) | 1990-02-20 | — | — | US | disclosed |
| CN-1039585-A | BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | SQUIBB & SONS INC (US) | 1990-02-14 | — | — | CN | disclosed |
| WO-1989012633-A1 | BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | E.R. SQUIBB & SONS, INC. (US) | 1989-12-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190247356-A1 | Aminocarbonylcarbamate Compounds | SLC6A3, SLC6A2, SLC6A4 | TRPA1 2438/4885OPRK1 8/4885ADRA2B 20/4885 |
| US-20150246874-A1 | AMINOCARBONYLCARBAMATE COMPOUNDS | SLC6A3, SLC6A2, SLC6A4 | TRPA1 2438/4885OPRK1 8/4885ADRA2B 20/4885 |
| US-10888542-B2 | Aminocarbonylcarbamate compounds | SLC6A3, SLC6A2, SLC6A4 | TRPA1 2438/4885OPRK1 8/4885ADRA2B 20/4885 |
| US-20160303067-A1 | AMINOCARBONYLCARBAMATE COMPOUNDS | SLC6A3, SLC6A2, SLC6A4 | TRPA1 2438/4885OPRK1 8/4885ADRA2B 20/4885 |
| US-20180085337-A1 | AMINOCARBONYLCARBAMATE COMPOUNDS | SLC6A3, SLC6A2, SLC6A4 | TRPA1 2438/4885OPRK1 8/4885ADRA2B 20/4885 |
| US-20210113514-A1 | AMINOCARBONYLCARBAMATE COMPOUNDS | SLC6A3, SLC6A2, SLC6A4 | TRPA1 2438/4885OPRK1 8/4885ADRA2B 20/4885 |
| US-20200046674-A1 | AMINOCARBONYLCARBAMATE COMPOUNDS | SLC6A3, SLC6A2, SLC6A4 | TRPA1 2438/4885OPRK1 8/4885ADRA2B 20/4885 |
| US-20230218562-A1 | AMINOCARBONYLCARBAMATE COMPOUNDS | SLC6A3, SLC6A2, SLC6A4 | TRPA1 2438/4885OPRK1 8/4885ADRA2B 20/4885 |
| US-10314808-B2 | Aminocarbonylcarbamate compounds | SLC6A3, SLC6A2, SLC6A4 | TRPA1 2438/4885OPRK1 8/4885ADRA2B 20/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.