Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | RAF1 | P04049 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
| ▸ | VCAM1 | P19320 | 3/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6821981 | 0.84 | VCAM1 (0.53) | LMNAMAPTALDH1A1HPGDMAPK1 | |
| SCHEMBL20302045 | 0.83 | NPSR1 (0.47) | LMNAMAPTALDH1A1HPGDMAPK1 | |
| SCHEMBL6981667 | 0.83 | KMT2A (0.51) | LMNAMAPTALDH1A1HPGDNPSR1 | |
| SCHEMBL4857830 | 0.83 | ALDH1A1 (0.49) | LMNAMAPTALDH1A1HPGDMAPK1 | |
| SCHEMBL4854941 | 0.80 | NPSR1 (0.47) | LMNAMAPTALDH1A1HPGDMAPK1 | |
| SCHEMBL15456899 | 0.80 | CHEK1 (0.49) | LMNAALDH1A1HPGDNPSR1KMT2A | |
| SCHEMBL4856254 | 0.80 | NPSR1 (0.47) | ALDH1A1HPGDMAPK1VCAM1NPSR1 | |
| SCHEMBL1627157 | 0.80 | CNR1 (0.51) | MAPTHPGDRAF1POLBCNR1 | |
| SCHEMBL18562538 | 0.79 | NPSR1 (0.46) | MAPTALDH1A1HPGDMAPK1NPSR1 | |
| SCHEMBL7652330 | 0.79 | SIRT6 (0.50) | LMNAMAPTALDH1A1HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250042870-A1 | DP ANTAGONIST | ONO PHARMACEUTICAL CO., LTD. (JP) | 2025-02-06 | — | — | US | disclosed |
| EP-3854781-B1 | DP ANTAGONISTS | ONO PHARMACEUTICAL CO (JP) | 2024-05-22 | — | — | EP | disclosed |
| US-20220204468-A1 | DP ANTAGONIST | ONO PHARMACEUTICAL CO., LTD. (JP) | 2022-06-30 | — | — | US | disclosed |
| US-11319296-B2 | DP antagonist | ONO PHARMACEUTICAL CO., LTD. (JP) | 2022-05-03 | — | — | US | disclosed |
| US-20220033371-A1 | DP ANTAGONIST | ONO PHARMACEUTICAL CO., LTD. (JP) | 2022-02-03 | — | — | US | disclosed |
| EP-3854781-A1 | DP ANTAGONIST | ONO Pharmaceutical Co., Ltd. (JP) | 2021-07-28 | — | — | EP | disclosed |
| WO-2020059790-A1 | DP ANTAGONIST | 小野薬品工業株式会社 | 2020-03-26 | — | — | WO | disclosed |
| EP-1666473-B1 | CARBOXYLIC ACID COMPOUNDS AND MEDICINAL COMPOSITIONS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO (JP) | 2013-01-02 | — | — | EP | disclosed |
| US-8138335-B2 | Carboxylic acid compounds and medicinal compositions containing the same as the active ingredient | ONO PHARMACEUTICAL CO., LTD (JP) | 2012-03-20 | — | — | US | disclosed |
| US-20100029631-A1 | CARBOXYLIC ACID COMPOUNDS AND MEDICINAL COMPOSITIONS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2010-02-04 | — | — | US | disclosed |
| US-7601712-B2 | Such as (1)-2-(4-chloro-3-((2-chloro-4-(((2S)-4-methyl-3,4-dihydro-2H-1,4-benzoxazin-2-ly)methoxy)benzoyl)amino)phenyl)-2-methylpropanoic acid; prostaglandin receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 2009-10-13 | — | — | US | disclosed |
| US-20070004716-A1 | Carboxylic acid compounds and medicinal compositions containing the same as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-01-04 | — | — | US | disclosed |
| CN-1882554-A | Carboxylic acid compounds and pharmaceutical compositions containing them as active ingredient | ONO PHARMACEUTICAL CO (JP) | 2006-12-20 | — | — | CN | disclosed |
| EP-1666473-A1 | CARBOXYLIC ACID COMPOUNDS AND MEDICINAL COMPOSITIONS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-06-07 | — | — | EP | disclosed |
| CN-1221538-C | Calcium salts of 1,5-benzodiazepine derivatives, process for producing salts and drugs containing same | ZERIA NEW PHARMACEUTICAL CO LT (JP) | 2005-10-05 | — | — | CN | disclosed |
| EP-1234818-B1 | CALCIUM SALTS OF 1,5-BENZODIAZEPINE DERIVATIVES, PROCESS FOR PRODUCING THE SALTS AND DRUGS CONTAINING THE SAME | ZERIA PHARM CO LTD (JP) | 2004-09-08 | — | — | EP | disclosed |
| US-6747022-B2 | TREATING DIGESTIVE TRACT DISEASE RESULTING FROM EXCESSIVE SECRETION OF GASTRIC ACID | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2004-06-08 | — | — | US | disclosed |
| US-20030096809-A1 | Calcium salts of 1,5-benzodiazepine derivatives, process for producing the salts and drugs containing the same | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2003-05-22 | — | — | US | disclosed |
| CN-1409706-A | Calcium salt of 1, 5-benzodiazepine * derivative, process for preparing the salt and pharmaceutical containing the salt | ZERIA PHARM CO LTD (JP) | 2003-04-09 | — | — | CN | disclosed |
| EP-1234818-A1 | CALCIUM SALTS OF 1,5-BENZODIAZEPINE DERIVATIVES, PROCESS FOR PRODUCING THE SALTS AND DRUGS CONTAINING THE SAME | Zeria Pharmaceutical Co., Ltd. (JP) | 2002-08-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220033371-A1 | DP ANTAGONIST | OPRL1, CNR1, NPSR1 | THRB 785/4885LMNA 2947/4885MAPT 3282/4885 |
| US-20100029631-A1 | CARBOXYLIC ACID COMPOUNDS AND MEDICINAL COMPOSITIONS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | GPR17, CYSLTR1, KIT | THRB 1586/4885LMNA 4266/4885MAPT 1750/4885 |
| US-20030096809-A1 | Calcium salts of 1,5-benzodiazepine derivatives, process for producing the salts and drugs containing the same | CCKBR, CCKAR, GABRB1 | THRB 290/4885LMNA 2877/4885MAPT 4232/4885 |
| US-20220204468-A1 | DP ANTAGONIST | OPRL1, CNR1, NPSR1 | THRB 785/4885LMNA 2947/4885MAPT 3282/4885 |
| US-20070004716-A1 | Carboxylic acid compounds and medicinal compositions containing the same as the active ingredient | GPR17, CYSLTR1, KIT | THRB 1586/4885LMNA 4266/4885MAPT 1750/4885 |
| US-11319296-B2 | DP antagonist | OPRL1, CNR1, NPSR1 | THRB 785/4885LMNA 2947/4885MAPT 3282/4885 |
| US-20250042870-A1 | DP ANTAGONIST | OPRL1, CNR1, NPSR1 | THRB 785/4885LMNA 2947/4885MAPT 3282/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.