Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.53 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.53 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 5/20 | 0.51 |
| ▸ | MAOA | P21397 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | NPY1R | P25929 | 1/20 | 0.49 |
| ▸ | NPY2R | P49146 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7235029 | 0.87 | TSHR (0.58) | SIGMAR1LMNAATMCARM1PRMT6 | |
| SCHEMBL7323463 | 0.84 | SIGMAR1 (0.64) | SIGMAR1LMNAMEN1KMT2AATM | |
| SCHEMBL29733117 | 0.83 | SIGMAR1 (0.85) | SIGMAR1LMNACARM1PRMT6PRMT8 | |
| SCHEMBL7225346 | 0.83 | SIGMAR1 (0.85) | SIGMAR1LMNACARM1PRMT6PRMT8 | |
| SCHEMBL1088446 | 0.81 | SIGMAR1 (0.74) | SIGMAR1LMNACARM1PRMT6PRMT8 | |
| SCHEMBL9686059 | 0.80 | SIGMAR1 (0.68) | SIGMAR1LMNACARM1PRMT6PRMT8 | |
| Hydrochloric Acid SCHEMBL1087168 | 0.79 | SIGMAR1 (0.71) | SIGMAR1LMNACARM1PRMT6PRMT8 | |
| SCHEMBL11795494 | 0.79 | LMNA (0.62) | SIGMAR1LMNAMEN1KMT2AATM | |
| SCHEMBL2749362 | 0.78 | SIGMAR1 (0.70) | SIGMAR1LMNAMEN1KMT2ACARM1 | |
| SCHEMBL5234462 | 0.78 | SIGMAR1 (0.65) | SIGMAR1LMNACARM1PRMT6PRMT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4918074-A | CALCIUM ANTAGONISTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-04-17 | — | — | US | disclosed |
| EP-0217142-A2 | A polyazaheterocyclic compound | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1987-04-08 | — | — | EP | disclosed |