SCHEMBL7325384

SCHEMBL7325384

O=CC(CC(=O)c1ccccc1)Cc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.50
MDM2 Q00987 1/20 0.49
SIGMAR1 Q99720 1/20 0.45
CAPN1 P07384 1/20 0.44
CYP1A2 P05177 1/20 0.44
KMT2A Q03164 3/20 0.44
TDP1 Q9NUW8 2/20 0.44
MEN1 O00255 2/20 0.44
MAPT P10636 2/20 0.44
HPGD P15428 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
KDM4E B2RXH2 1/20 0.44
CYP3A4 P08684 1/20 0.44
ALOX15 P16050 1/20 0.44
CES1 P23141 1/20 0.44
MAPK1 P28482 1/20 0.44
CPA1 P15085 2/20 0.43
NPC1 O15118 2/20 0.43
CASP3 P42574 1/20 0.43
RAB9A P51151 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24157492 1.00 TSHR (0.50) TSHRMDM2SIGMAR1CAPN1CYP1A2
SCHEMBL24157470 0.89 MAPT (0.55) KMT2AMAPTCES1KMOL3MBTL1
SCHEMBL24157467 0.89 MAPT (0.55) KMT2AMAPTCES1KMOL3MBTL1
SCHEMBL1915970 0.84 CPA3 (0.56) MDM2CYP1A2CPA1CPB1CPA3
SCHEMBL13752834 0.83 PTPN1 (0.56) KMT2ATDP1MEN1KDM4ENPC1
SCHEMBL7266299 0.79 EPHX1 (0.54) MDM2SIGMAR1CYP1A2KMT2AMEN1
SCHEMBL7327052 0.79 LMNA (0.45) TSHRCYP1A2KMT2AMAPTSMN1; SMN2
SCHEMBL23219194 0.78 ALPI (0.44) MDM2CYP1A2CPA1CPB1CPA3
SCHEMBL7328940 0.78 CYP1A2 (0.43) MDM2CYP1A2KMT2AMEN1CPA1
SCHEMBL6446630 0.77 CPA1 (0.43) MDM2CYP1A2KMT2AMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210402380-A1 PEROVSKITES FOR PHOTOCATALYTIC ORGANIC SYNTHESIS SAN DIEGO STATE UNIVERSITY FOUNDATION (US) 2021-12-30 US disclosed
EP-0292800-A2 Amino acid derivatives MERCK PATENT GmbH (DE) 1988-11-30 EP disclosed
EP-0249096-A2 Renin-inhibiting amino acid derivatives MERCK PATENT GmbH (DE) 1987-12-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210402380-A1 PEROVSKITES FOR PHOTOCATALYTIC ORGANIC SYNTHESIS CBR3, SCO2, CRY2 TSHR 2749/4885MDM2 4516/4885SIGMAR1 3198/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.