Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 11/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8111507 | 0.82 | MGLL (0.47) | MGLLLMNATP53MAPTL3MBTL1 | |
| SCHEMBL2297101 | 0.75 | MGLL (0.58) | MGLLLMNATP53MAPTL3MBTL1 | |
| SCHEMBL4671309 | 0.75 | MGLL (0.43) | MGLLLMNATP53MAPTL3MBTL1 | |
| SCHEMBL8149178 | 0.74 | MGLL (0.48) | MGLLLMNATP53MAPTL3MBTL1 | |
| SCHEMBL4674723 | 0.73 | LMNA (0.46) | MGLLLMNATP53MAPTL3MBTL1 | |
| SCHEMBL8106007 | 0.73 | MGLL (0.44) | MGLLLMNATP53MAPTL3MBTL1 | |
| SCHEMBL8109646 | 0.72 | MGLL (0.43) | MGLLLMNATP53MAPTL3MBTL1 | |
| SCHEMBL8140788 | 0.72 | ALDH1A1 (0.48) | MGLLLMNATP53MAPTL3MBTL1 | |
| SCHEMBL4671256 | 0.72 | MGLL (0.46) | MGLLLMNATP53MAPTL3MBTL1 | |
| SCHEMBL7325935 | 0.72 | MGLL (0.46) | MGLLLMNATP53MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376506-B1 | REACTING SULFAMOYL OXAZOLIDONE WITH (1,2,3,4)-TETRAHYDRO-BETA-CARBOLINE TO FORM INHIBITOR; USED TO TREAT ARTHRITIS, OSTEOPOROSIS, PERIODONTAL DISEASE, CARDIOVASCULAR DISEASES, MULTIPLE SCLEROSIS, AND TUMORS | SYNTEX (U.S.A.) LLC | 2002-04-23 | — | — | US | disclosed |