Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | REN | P00797 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9220946 | 0.90 | L3MBTL1 (0.46) | CPB2LTA4HENPEPL3MBTL1ALDH1A1 | |
| SCHEMBL7325963 | 0.79 | CTSS (0.50) | CPB2CTSKRENCTSD | |
| SCHEMBL10774125 | 0.75 | CTSS (0.44) | CPB2CTSKRENCTSD | |
| SCHEMBL17792791 | 0.71 | METAP2 (0.42) | ENPEPCTSKRENMETAP2ALDH1A1 | |
| SCHEMBL5520876 | 0.70 | ENPEP (0.46) | ENPEPL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL5520878 | 0.70 | ENPEP (0.46) | ENPEPL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL15892241 | 0.69 | METAP2 (0.45) | CPB2LTA4HRENMETAP2CHRNB2 | |
| SCHEMBL2715742 | 0.69 | ALOX5 (0.48) | METAP2EPHX1 | |
| SCHEMBL842505 | 0.69 | ALOX5 (0.48) | METAP2EPHX1 | |
| SCHEMBL4319266 | 0.69 | ALOX5 (0.48) | METAP2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292800-A2 | Amino acid derivatives | MERCK PATENT GmbH (DE) | 1988-11-30 | — | — | EP | disclosed |
| EP-0249096-A2 | Renin-inhibiting amino acid derivatives | MERCK PATENT GmbH (DE) | 1987-12-16 | — | — | EP | disclosed |