Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7326635 | 0.75 | MMP3 (0.39) | ALDH1A1RAB9AGAASMN1; SMN2 | |
| SCHEMBL7326300 | 0.70 | SMYD2 (0.37) | DDB1CRBNMEN1NPC1RAB9A | |
| SCHEMBL136822 | 0.62 | NPC1 (0.60) | DDB1CRBNALDH1A1MEN1NPC1 | |
| SCHEMBL18398 | 0.62 | MAPK1 (0.36) | ALDH1A1MEN1KMT2AGAAMAPT | |
| SCHEMBL30367101 | 0.60 | MAPK1 (0.35) | ALDH1A1MEN1KMT2AGAAMAPT | |
| Hydrochloric Acid SCHEMBL1295227 | 0.60 | MAPK1 (0.35) | ALDH1A1MEN1KMT2AGAAMAPT | |
| Phosphoric Acid SCHEMBL28944728 | 0.60 | TSHR (0.41) | ALDH1A1MEN1KMT2AGAAMAPT | |
| Glycerin SCHEMBL4294890 | 0.59 | LMNA (0.36) | ALDH1A1 | |
| Isobutane SCHEMBL28190489 | 0.58 | CYP1A2 (0.37) | ALDH1A1MEN1KMT2AGAAMAPT | |
| SCHEMBL1750928 | 0.57 | NPC1 (0.52) | DDB1CRBNALDH1A1MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470849-A | Anticoagulants | SMITHKLINE BEECHAM CORP. (US) | 1995-11-28 | — | — | US | disclosed |
| EP-0557406-A4 | -G(G)-TURN PEPTIDOMIMETICS AS FIBRINOGEN ANTAGONISTS | — | 1993-10-06 | — | — | EP | disclosed |
| EP-0557406-A1 | GAMMA-TURN PEPTIDOMIMETICS AS FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-09-01 | — | — | EP | disclosed |
| WO-1992007568-A1 | η-TURN PEPTIDOMIMETICS AS FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1992-05-14 | — | — | WO | disclosed |