Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | NPC1L1 | Q9UHC9 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 6/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 6/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.33 |
| ▸ | ACHE | P22303 | 3/20 | 0.33 |
| ▸ | DRD2 | P14416 | 3/20 | 0.33 |
| ▸ | DRD4 | P21917 | 3/20 | 0.33 |
| ▸ | DRD3 | P35462 | 3/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8299798 | 0.76 | MMP3 (0.45) | MMP3MMP8METAP2MMP2MMP9 | |
| SCHEMBL7326308 | 0.75 | DDB1 (0.33) | ALDH1A1SMN1; SMN2GAARAB9A | |
| SCHEMBL7326631 | 0.70 | SMYD2 (0.43) | ALDH1A1TSHRSMN1; SMN2LMNASTAT3 | |
| SCHEMBL1660708 | 0.68 | NPC1 (0.43) | ALDH1A1ACHETSHRSMN1; SMN2RAB9A | |
| SCHEMBL18155147 | 0.67 | MBTD1 (0.49) | MMP3MMP8ALDH1A1CHRM2CHRM4 | |
| SCHEMBL7576221 | 0.65 | ROCK2 (0.44) | ALDH1A1TSHRRAB9A | |
| SCHEMBL14275864 | 0.64 | RAB9A (0.46) | ALDH1A1TSHRSMN1; SMN2LMNASTAT3 | |
| SCHEMBL136822 | 0.62 | NPC1 (0.60) | ALDH1A1TSHRSMN1; SMN2KDM4EGAA | |
| SCHEMBL1661092 | 0.62 | BPTF (0.44) | CHRM2CHRM1CHRM3ACHERAB9A | |
| SCHEMBL18398 | 0.62 | MAPK1 (0.36) | ALDH1A1ACHETSHRGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470849-A | Anticoagulants | SMITHKLINE BEECHAM CORP. (US) | 1995-11-28 | — | — | US | disclosed |
| EP-0557406-A4 | -G(G)-TURN PEPTIDOMIMETICS AS FIBRINOGEN ANTAGONISTS | — | 1993-10-06 | — | — | EP | disclosed |
| EP-0557406-A1 | GAMMA-TURN PEPTIDOMIMETICS AS FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-09-01 | — | — | EP | disclosed |
| WO-1992007568-A1 | η-TURN PEPTIDOMIMETICS AS FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1992-05-14 | — | — | WO | disclosed |