Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.53 |
| ▸ | LTA4H | P09960 | 11/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPY1R | P25929 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7327514 | 0.94 | LTA4H (0.52) | HRH3LTA4HNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7331294 | 0.91 | NPC1 (0.57) | HRH3LTA4HNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7324866 | 0.87 | PPARA (0.58) | LTA4HNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL7330398 | 0.81 | HRH3 (0.60) | HRH3LTA4HNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7324364 | 0.80 | HRH3 (0.59) | HRH3LTA4HNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7449615 | 0.79 | HPGD (0.54) | HRH3NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL7328905 | 0.79 | KDM4E (0.53) | HRH3NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL7326386 | 0.76 | GPR119 (0.61) | LTA4HKDM4E | |
| SCHEMBL5646504 | 0.75 | KMT2A (0.70) | HRH3LTA4HNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7326383 | 0.75 | LTA4H (0.49) | LTA4HALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0674514-A1 | USE OF ARYLOXYALKYL SUBSTITUTED CYCLIC AMINES AS CALCIUM CHANNEL ANTAGONISTS AND NEW PHENYLOXYALKYL PIPERIDIN DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 1995-10-04 | — | — | EP | disclosed |
| WO-1994013291-A1 | USE OF ARYLOXYALKYL SUBSTITUTED CYCLIC AMINES AS CALCIUM CHANNEL ANTAGONISTS AND NEW PHENYLOXYALKYL PIPERIDIN DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 1994-06-23 | — | — | WO | disclosed |