Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | PGR | P06401 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7335926 | 0.91 | NR3C1 (0.64) | NR3C1LMNAMAPTMEN1KMT2A | |
| SCHEMBL7331497 | 0.88 | NR3C1 (0.58) | NR3C1LMNAMAPTMEN1KMT2A | |
| SCHEMBL8543953 | 0.85 | NR3C1 (0.58) | NR3C1LMNAMAPTMEN1KMT2A | |
| SCHEMBL7326548 | 0.82 | NR3C1 (0.60) | NR3C1LMNAMAPTESR1PGR | |
| SCHEMBL8549210 | 0.81 | NR3C1 (0.64) | NR3C1LMNAMAPTMEN1KMT2A | |
| SCHEMBL8544327 | 0.80 | PGR (0.56) | NR3C1LMNAMEN1KMT2AESR1 | |
| SCHEMBL7330183 | 0.80 | CA12 (0.50) | MEN1KMT2APGRS1PR1L3MBTL1 | |
| SCHEMBL8549652 | 0.80 | ESR1 (0.66) | NR3C1LMNAMAPTMEN1KMT2A | |
| SCHEMBL6553024 | 0.79 | PKM (0.75) | NR3C1LMNAMAPTMEN1KMT2A | |
| SCHEMBL7336428 | 0.76 | NR3C1 (0.58) | NR3C1LMNAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1046710-C | New 4-aminopyridines, process for preparing the same and medicaments containing the same | LUOHE DIAGNOSTIC EQUIPMENT CO (DE) | 1999-11-24 | — | — | CN | disclosed |
| EP-0687253-B1 | 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1998-12-16 | — | — | EP | disclosed |
| CN-1119858-A | Aminopyridines, process for their preparation and pharmaceutical compositions containing them | BOEHRINGER MANNHEIM GMBH (DE) | 1996-04-03 | — | — | CN | disclosed |
| EP-0687253-A1 | NEW 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | Roche Diagnostics GmbH (DE) | 1995-12-20 | — | — | EP | disclosed |
| WO-1994020467-A1 | NEW 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1994-09-15 | — | — | WO | disclosed |