Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 5/20 | 0.58 |
| ▸ | PGR | P06401 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | CNR1 | P21554 | 2/20 | 0.55 |
| ▸ | CNR2 | P34972 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7335926 | 0.88 | NR3C1 (0.64) | NR3C1LMNAPGRALDH1A1NPSR1 | |
| SCHEMBL8543953 | 0.85 | NR3C1 (0.58) | NR3C1LMNAPGRALDH1A1NPSR1 | |
| SCHEMBL7326995 | 0.82 | NR3C1 (0.58) | NR3C1LMNAPGRALDH1A1CNR1 | |
| SCHEMBL7328298 | 0.82 | PGR (0.53) | LMNAPGRMAPT | |
| SCHEMBL7335030 | 0.82 | PGR (0.63) | NR3C1LMNAPGRALDH1A1NPSR1 | |
| SCHEMBL7326459 | 0.81 | PGR (0.62) | NR3C1LMNAPGRALDH1A1NPSR1 | |
| SCHEMBL8549210 | 0.78 | NR3C1 (0.64) | NR3C1LMNAPGRALDH1A1NPSR1 | |
| SCHEMBL9703044 | 0.77 | LMNA (0.60) | NR3C1LMNAALDH1A1NPSR1CNR1 | |
| SCHEMBL6553024 | 0.76 | PKM (0.75) | NR3C1LMNAALDH1A1MAPTESR1 | |
| SCHEMBL7335037 | 0.75 | NR3C1 (0.58) | NR3C1LMNAPGRALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687253-B1 | 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1998-12-16 | — | — | EP | disclosed |
| EP-0687253-A1 | NEW 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | Roche Diagnostics GmbH (DE) | 1995-12-20 | — | — | EP | disclosed |
| WO-1994020467-A1 | NEW 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1994-09-15 | — | — | WO | disclosed |