Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 6/20 | 0.64 |
| ▸ | PKM | P14618 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.49 |
| ▸ | PTGES | O14684 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | RORC | P51449 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7335037 | 0.91 | NR3C1 (0.58) | NR3C1PKMLMNAMAPTESR1 | |
| SCHEMBL7336428 | 0.91 | NR3C1 (0.58) | NR3C1PKMLMNAMAPTESR1 | |
| SCHEMBL7331497 | 0.91 | NR3C1 (0.58) | NR3C1PKMLMNAMAPTESR1 | |
| SCHEMBL6553024 | 0.89 | PKM (0.75) | NR3C1PKMLMNAMAPTESR1 | |
| SCHEMBL7335926 | 0.89 | NR3C1 (0.64) | NR3C1PKMLMNAMAPTESR1 | |
| SCHEMBL8543953 | 0.81 | NR3C1 (0.58) | NR3C1PKMLMNAMAPTESR1 | |
| SCHEMBL7326995 | 0.81 | NR3C1 (0.58) | NR3C1PKMLMNAMAPTESR1 | |
| SCHEMBL5330652 | 0.78 | ESR1 (0.78) | NR3C1PKMLMNAESR1MEN1 | |
| SCHEMBL7326548 | 0.78 | NR3C1 (0.60) | NR3C1PKMLMNAMAPTESR1 | |
| SCHEMBL9703044 | 0.77 | LMNA (0.60) | NR3C1PKMLMNAMAPTESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687253-B1 | 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1998-12-16 | — | — | EP | disclosed |