Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | XIAP | P98170 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | PYGL | P06737 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7324240 | 0.78 | MEN1 (0.57) | ALDH1A1KMT2AMEN1L3MBTL1CYP1A2 | |
| SCHEMBL7330405 | 0.71 | TRPA1 (0.39) | LMNACYP1B1 | |
| SCHEMBL7322107 | 0.70 | L3MBTL1 (0.52) | KMT2AMEN1L3MBTL1KDM4E | |
| SCHEMBL7477378 | 0.70 | SIRT1 (0.48) | LMNAALDH1A1KMT2AMEN1PKM | |
| SCHEMBL29352010 | 0.70 | ALDH1A1 (0.54) | LMNAALDH1A1KMT2AMEN1PKM | |
| SCHEMBL4625520 | 0.68 | ALDH1A1 (0.69) | ALDH1A1KMT2AMEN1PKMCYP1B1 | |
| SCHEMBL41923 | 0.67 | ALDH1A1 (0.64) | LMNAALDH1A1KMT2AMEN1PKM | |
| SCHEMBL30711693 | 0.67 | ALDH1A1 (1.00) | LMNAALDH1A1KMT2AMEN1PKM | |
| SCHEMBL2959641 | 0.67 | ALDH1A1 (1.00) | LMNAALDH1A1KMT2AMEN1PKM | |
| SCHEMBL8314773 | 0.66 | ALDH1A1 (0.72) | LMNAALDH1A1KMT2AMEN1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5075304-A | Nervous system disorders | NOVO NORDISK A/S (DK) | 1991-12-24 | — | — | US | disclosed |
| EP-0344943-A1 | Imidazoquinoxaline compounds and their preparation and use | NOVO NORDISK A/S (DK) | 1989-12-06 | — | — | EP | disclosed |