Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7471730 | 0.77 | OPRL1 (0.42) | TRPA1SCN9AOPRL1CYP1B1 | |
| SCHEMBL4420923 | 0.77 | OPRL1 (0.42) | TRPA1SCN9AOPRL1CYP1B1 | |
| SCHEMBL7324240 | 0.76 | MEN1 (0.57) | — | |
| SCHEMBL7331291 | 0.74 | ALDH1A1 (0.50) | LMNA | |
| SCHEMBL4995780 | 0.73 | OPRL1 (0.41) | TRPA1SCN9AOPRL1CYP1B1 | |
| SCHEMBL8025052 | 0.73 | OPRL1 (0.41) | TRPA1SCN9AOPRL1CYP1B1 | |
| SCHEMBL7329951 | 0.73 | L3MBTL1 (0.49) | LMNA | |
| SCHEMBL7323195 | 0.72 | TSHR (0.54) | LMNA | |
| SCHEMBL7329003 | 0.71 | LMNA (0.55) | LMNACYP1B1 | |
| SCHEMBL19410658 | 0.70 | OPRM1 (0.45) | TRPA1SCN9AOPRL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5075304-A | Nervous system disorders | NOVO NORDISK A/S (DK) | 1991-12-24 | — | — | US | disclosed |
| EP-0344943-A1 | Imidazoquinoxaline compounds and their preparation and use | NOVO NORDISK A/S (DK) | 1989-12-06 | — | — | EP | disclosed |