Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 9/20 | 0.46 |
| ▸ | CTSB | P07858 | 8/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 1/20 | 0.40 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.40 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7321477 | 0.89 | CASP1 (0.46) | CASP1CTSD | |
| SCHEMBL7329312 | 0.87 | CTSD (0.42) | CASP1CTSD | |
| SCHEMBL7322813 | 0.84 | CTSD (0.37) | CASP1CA2CA5ACTSD | |
| SCHEMBL7323405 | 0.84 | SYK (0.46) | CTSKCTSBCASP1RENCTSD | |
| SCHEMBL7329206 | 0.83 | CTSB (0.42) | CTSKCTSBCAPN1CAPN2 | |
| SCHEMBL9297033 | 0.83 | CTSB (0.42) | CTSKCTSBCASP1CA2CA5A | |
| SCHEMBL7327018 | 0.81 | CASP1 (0.47) | CASP1CTSD | |
| SCHEMBL9296228 | 0.81 | CASP1 (0.54) | CASP1CTSD | |
| SCHEMBL7332099 | 0.81 | LNPEP (0.37) | CTSKCTSBCASP1CA2CA5A | |
| SCHEMBL9296340 | 0.80 | CTSB (0.42) | CTSKCTSBCASP1CA2CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990000399-A1 | RETROVIRAL PROTEASE BINDING PEPTIDES | SMITHKLINE BECKMAN CORPORATION (US) | 1990-01-25 | — | — | WO | disclosed |
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |