Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 5/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7329332 | 0.81 | MEN1 (0.42) | ALDH1A1KDM4EGAAALPLAR | |
| SCHEMBL14336359 | 0.81 | RECQL (0.42) | ALDH1A1KDM4EGAAALPLAR | |
| SCHEMBL5201507 | 0.81 | ALDH1A1 (0.40) | ALDH1A1KDM4EGAAALPLAR | |
| SCHEMBL5200701 | 0.77 | KDM4E (0.54) | ALDH1A1KDM4EGAAPOLBHTT | |
| SCHEMBL10472405 | 0.77 | POLB (0.37) | ALDH1A1KDM4EGAAALPLAR | |
| SCHEMBL10472768 | 0.75 | ALDH1A1 (0.37) | ALDH1A1KDM4EGAAPOLBHSD17B10 | |
| SCHEMBL7326712 | 0.75 | RAB9A (0.53) | ALDH1A1KDM4EGAAHPGDHSD17B10 | |
| SCHEMBL30046397 | 0.73 | HTR1A (0.51) | ALDH1A1KDM4EGAAPOLBHTT | |
| SCHEMBL11548784 | 0.73 | HTR1A (0.51) | ALDH1A1KDM4EGAAPOLBHTT | |
| SCHEMBL15091185 | 0.68 | ALDH1A1 (0.40) | ALDH1A1KDM4EGAAALPLAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102890-A | Anxiolytic agents | RHONE-POULENC SANTE (FR) | 1992-04-07 | — | — | US | disclosed |
| US-4960779-A | Pyrrole derivatives, and pharmaceutical compositions which contain them and pharmacological methods of use | RHONE-POULENC SANTE (FR) | 1990-10-02 | — | — | US | disclosed |
| US-4016274-A | TRANQUILIZERS AND ANTICONVULSANT AGENTS | RHONE-POULENC S.A. (FR) | 1977-04-05 | — | — | US | disclosed |