Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7331291 | 0.74 | ALDH1A1 (0.50) | L3MBTL1KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL7330405 | 0.73 | TRPA1 (0.39) | LMNA | |
| SCHEMBL8563447 | 0.72 | KDM1A (0.45) | KDM1AKDM4EMAPT | |
| SCHEMBL7324240 | 0.71 | MEN1 (0.57) | L3MBTL1ALDH1A1MEN1POLBKMT2A | |
| SCHEMBL29924011 | 0.69 | CHRM2 (0.47) | KDM1AKDM4EMAPT | |
| SCHEMBL9044824 | 0.69 | HTR7 (0.66) | KDM1A | |
| SCHEMBL4624294 | 0.69 | ALDH1A1 (0.78) | KDM1AKDM4EMAPTALDH1A1CA1 | |
| SCHEMBL8564644 | 0.69 | CCKBR (0.49) | KDM1AKDM4EMAPT | |
| SCHEMBL8556230 | 0.68 | GRM5 (0.66) | L3MBTL1KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL29525355 | 0.68 | DRD2 (0.67) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5075304-A | Nervous system disorders | NOVO NORDISK A/S (DK) | 1991-12-24 | — | — | US | disclosed |
| EP-0344943-A1 | Imidazoquinoxaline compounds and their preparation and use | NOVO NORDISK A/S (DK) | 1989-12-06 | — | — | EP | disclosed |