Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 9/20 | 0.60 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7320813 | 0.93 | PRSS1 (0.53) | PRSS1TMPRSS15MAPTPOLBTP53 | |
| SCHEMBL7319750 | 0.81 | PRSS1 (0.66) | PRSS1TMPRSS15MAPTPOLBLMNA | |
| SCHEMBL11829181 | 0.80 | KMT2A (0.42) | MAPTHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL29246356 | 0.80 | SMN1; SMN2 (0.41) | MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9027345 | 0.79 | RAB9A (0.54) | MAPTPOLBHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL7330416 | 0.77 | PRSS1 (0.61) | PRSS1TMPRSS15MAPTLMNAALDH1A1 | |
| SCHEMBL10804963 | 0.76 | MEN1 (0.48) | MAPTHTTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL7329837 | 0.76 | PRSS1 (0.63) | PRSS1TMPRSS15MAPTPOLBHTT | |
| SCHEMBL8315096 | 0.76 | MAPT (0.51) | MAPTPOLBTP53HTTLMNA | |
| SCHEMBL7329001 | 0.75 | PRSS1 (0.59) | PRSS1TMPRSS15MAPTPOLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4570006-A | ANTITHROMBIN; ENZYME AND HORMONE INHIBITORS | TORII & CO. LTD. (JP) | 1986-02-11 | — | — | US | disclosed |
| US-4514416-A | Amidine compound, process for producing same and anti-complement agent comprising same | TORII & CO. LTD. (JP) | 1985-04-30 | — | — | US | disclosed |