SCHEMBL733350

SCHEMBL733350

CC(=O)C(C)C(=S)ON1C(=O)CCC1=O

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 3/20 0.32
GLA P06280 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1541732 0.81 MGLL (0.33) MGLLGLA
SCHEMBL863100 0.81 MGLL (0.33) MGLLGLA
SCHEMBL4618888 0.74 GLA (0.32) MGLLGLA
SCHEMBL18510166 0.72 GLA (0.41) MGLLGLA
SCHEMBL30699 0.72 GLA (0.41) MGLLGLA
SCHEMBL30779753 0.72 GLA (0.41) MGLLGLA
SCHEMBL258692 0.71 MGLL (0.36) MGLLGLA
SCHEMBL17430432 0.71 MGLL (0.36) MGLLGLA
SCHEMBL9010906 0.70 MGLL (0.33) MGLLGLA
Hydrogen Sulfide SCHEMBL28436920 0.70 GLA (0.40) MGLLGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 168 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104548118-A Antibodized covalent modified poloxamer copolymer and preparation method and applications thereof UNIV SOUTHEAST 2015-04-29 CN claimed
WO-2010078376-A2 FC-SPECIFIC POLYMER-CONJUGATED ANTIBODIES AND THEIR DIAGNOSTIC USE VENTANA MEDICAL SYSTEMS, INC. (US) 2010-07-08 WO claimed
EP-0382781-B1 COMPOSITION FOR TREATING CANCERS CHARACTERIZED BY OVER-EXPRESSION OF THE C-FMS PROTO-ONCOGENE GENETICS INSTITUTE, INC. (US) 1993-09-29 EP claimed
US-20260109728-A1 IMMUNOMODULATING POLYNUCLEOTIDES, ANTIBODY CONJUGATES THEREOF, AND METHODS OF THEIR USE TALLAC THERAPEUTICS INC (US) 2026-04-23 US disclosed
US-12351598-B2 Immunomodulating polynucleotides, antibody conjugates thereof, and methods of their use Tallac Therapeutics, Inc. (US) 2025-07-08 US disclosed
US-12280021-B2 Affinity medicant conjugate AF CHEMICALS, LLC (US) 2025-04-22 US disclosed
EP-4257186-B1 AFFINITY MEDICANT CONJUGATES AF CHEMICALS LLC (US) 2024-12-04 EP disclosed
US-20230372267-A1 AFFINITY MEDICANT CONJUGATE Califia Pharma Inc. (US) 2023-11-23 US disclosed
EP-4257186-A2 AFFINITY MEDICANT CONJUGATES AF Chemicals LLC (US) 2023-10-11 EP disclosed
EP-3129357-B1 AFFINITY MEDICANT CONJUGATES AF CHEMICALS LLC (US) 2023-08-23 EP disclosed
US-11359185-B2 Antibody conjugates VENTANA MEDICAL SYSTEMS, INC. (US) 2022-06-14 US disclosed
WO-2002082078-A2 ACTIVATED ENZYME-LINKED DETECTION SYSTEMS FOR DETECTING AND QUANTIFYING NUCLEID ACIDS, ANTIGENS ANTIBODIES AND OTHER ANALYTES FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 2002-10-17 WO disclosed
WO-2002081739-A2 NON-ENZYMATIC LIPOSOME-LINKED CLOSELY SPACED ARRAY ELECTRODES ASSAY (NEL-ELA) FOR DETECTING AND QUANTIFYING NUCLEIC ACIDS Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2002-10-17 WO disclosed
WO-2002081738-A2 SYSTEM AND METHOD FOR DETECTING AND QUANTIFYING NUCLEIC ACIDS USING COVALENT BINDING FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 2002-10-17 WO disclosed
US-20020048598-A1 INTERNALLY SUPPORTED LIPID VESICLE SYSTEMS MALIK NAVID (GB) 2002-04-25 US disclosed
US-20020006623-A1 Compositions and methods for array-based genomic nucleic acid analysis of biological molecules NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2002-01-17 US disclosed
WO-2001041827-A1 INTERNALLY SUPPORTED BIOMIMETIC MATERIALS AND COATINGS MALIK NAVID (GB) 2001-06-14 WO disclosed
EP-0998267-A1 INTERNALLY SUPPORTED LIPID VESICLE SYSTEMS Malik, Navid (GB) 2000-05-10 EP disclosed
WO-1998056353-A1 INTERNALLY SUPPORTED LIPID VESICLE SYSTEMS MALIK NAVID (GB) 1998-12-17 WO disclosed
EP-0382781-B1 COMPOSITION FOR TREATING CANCERS CHARACTERIZED BY OVER-EXPRESSION OF THE C-FMS PROTO-ONCOGENE GENETICS INSTITUTE, INC. (US) 1993-09-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12280021-B2 Affinity medicant conjugate FCER2, HDGF, FCGR2A MGLL 1795/4885GLA 3201/4885
US-20230372267-A1 AFFINITY MEDICANT CONJUGATE FCER2, HDGF, FCGR2A MGLL 1795/4885GLA 3201/4885
US-20020048598-A1 INTERNALLY SUPPORTED LIPID VESICLE SYSTEMS STARD3, CHMP4B, EXOSC10 MGLL 6/4885GLA 3787/4885
US-12351598-B2 Immunomodulating polynucleotides, antibody conjugates thereof, and methods of their use TYMP, DUT, PAICS MGLL 4149/4885GLA 3566/4885
US-20260109728-A1 IMMUNOMODULATING POLYNUCLEOTIDES, ANTIBODY CONJUGATES THEREOF, AND METHODS OF THEIR USE UNG, DUT, TYMP MGLL 4778/4885GLA 2778/4885
US-20020006623-A1 Compositions and methods for array-based genomic nucleic acid analysis of biological molecules XRN2, XPA, XRCC6 MGLL 3642/4885GLA 2045/4885
US-11359185-B2 Antibody conjugates BCR, CD2BP2, EPCAM MGLL 3100/4885GLA 1522/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.