Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | F11 | P03951 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MLYCD | O95822 | 1/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7336287 | 0.89 | SMN1; SMN2 (0.43) | NPSR1ALDH1A1KMT2APKMMTNR1B | |
| SCHEMBL7332346 | 0.89 | LMNA (0.40) | NPSR1ALDH1A1KMT2AMTNR1BRAB9A | |
| SCHEMBL7333518 | 0.84 | MLYCD (0.45) | ALDH1A1KMT2AMTNR1BHPGDHTT | |
| SCHEMBL7338363 | 0.83 | ALDH1A1 (0.42) | NPSR1ALDH1A1KMT2ARAB9AHPGD | |
| SCHEMBL7339841 | 0.83 | ALDH1A1 (0.44) | NPSR1ALDH1A1KMT2ARAB9AHPGD | |
| SCHEMBL7331572 | 0.83 | ALDH1A1 (0.47) | NPSR1ALDH1A1KMT2APKMRAB9A | |
| SCHEMBL7343524 | 0.83 | F11 (0.45) | NPSR1ALDH1A1RAB9AHPGDHTT | |
| SCHEMBL7341144 | 0.83 | IMPDH2 (0.44) | NPSR1ALDH1A1KMT2ARAB9AHPGD | |
| SCHEMBL7342249 | 0.82 | ADRB1 (0.47) | NPSR1ALDH1A1KMT2ARAB9AHPGD | |
| SCHEMBL7333593 | 0.82 | F11 (0.49) | F11KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0475531-B1 | Benzoic acid phenylester compounds and elastase inhibiting compositions containing the same | ASAHI CHEMICAL IND (JP) | 1995-01-18 | — | — | EP | disclosed |
| EP-0475531-A1 | Benzoic acid phenylester compounds and elastase inhibiting compositions containing the same | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1992-03-18 | — | — | EP | disclosed |