Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.47 |
| ▸ | PARP1 | P09874 | 4/20 | 0.44 |
| ▸ | HTR1A | P08908 | 3/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | HTR7 | P34969 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7304514 | 0.88 | SMN1; SMN2 (0.41) | SIGMAR1PARP1KDM4E | |
| SCHEMBL7335487 | 0.79 | SIGMAR1 (0.47) | SIGMAR1PARP1HTR1AHTR7HTR2A | |
| SCHEMBL7300628 | 0.76 | MITF (0.39) | SIGMAR1PARP1S1PR1S1PR3KDM4E | |
| Maleic Acid SCHEMBL9375437 | 0.73 | SIGMAR1 (0.46) | SIGMAR1PARP1HTR1AHTR7KDM4E | |
| Fumaric Acid SCHEMBL9375443 | 0.73 | SIGMAR1 (0.46) | SIGMAR1PARP1HTR1AHTR7KDM4E | |
| SCHEMBL11710522 | 0.72 | HTR1A (0.60) | SIGMAR1PARP1HTR1AHTR7HTR2A | |
| SCHEMBL7333358 | 0.71 | HTR1A (0.48) | SIGMAR1PARP1HTR1AHTR7KDM4E | |
| SCHEMBL10231292 | 0.70 | SIGMAR1 (0.68) | SIGMAR1HTR1AS1PR1S1PR3KMT2A | |
| SCHEMBL9372501 | 0.69 | SIGMAR1 (0.52) | SIGMAR1PARP1HTR1A | |
| SCHEMBL7299309 | 0.69 | SIGMAR1 (0.49) | SIGMAR1PARP1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5149817-A | Psychotropic agents | SHIONOGI & CO., LTD. (JP) | 1992-09-22 | — | — | US | disclosed |
| EP-0445701-A1 | Novel tetrahydropyridine derivatives | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1991-09-11 | — | — | EP | disclosed |