Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.38 |
| ▸ | PPARG | P37231 | 3/20 | 0.37 |
| ▸ | PPARA | Q07869 | 3/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7304514 | 0.88 | SMN1; SMN2 (0.41) | MITFSMN1; SMN2SIGMAR1PPARGPPARA | |
| SCHEMBL7335481 | 0.76 | SIGMAR1 (0.47) | SIGMAR1KDM4ES1PR1S1PR3PARP1 | |
| SCHEMBL7305975 | 0.72 | SIGMAR1 (0.54) | SIGMAR1KDM4E | |
| SCHEMBL9735887 | 0.69 | PARP1 (0.45) | SIGMAR1PPARGPPARADRD2PARP1 | |
| SCHEMBL7333358 | 0.68 | HTR1A (0.48) | SIGMAR1DRD2KDM4EPARP1 | |
| SCHEMBL7300624 | 0.68 | ALDH1A1 (0.42) | SMN1; SMN2SIGMAR1PPARGPPARADRD2 | |
| SCHEMBL7304603 | 0.68 | SIGMAR1 (0.45) | SMN1; SMN2SIGMAR1PPARGPPARADRD2 | |
| SCHEMBL7304853 | 0.67 | SIGMAR1 (0.58) | SIGMAR1 | |
| SCHEMBL4237702 | 0.67 | SIGMAR1 (0.54) | SIGMAR1DRD2KDM4E | |
| SCHEMBL9372501 | 0.66 | SIGMAR1 (0.52) | SIGMAR1DRD2PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5149817-A | Psychotropic agents | SHIONOGI & CO., LTD. (JP) | 1992-09-22 | — | — | US | disclosed |
| EP-0445701-A1 | Novel tetrahydropyridine derivatives | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1991-09-11 | — | — | EP | disclosed |