Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 10/20 | 0.52 |
| ▸ | CTSB | P07858 | 4/20 | 0.52 |
| ▸ | CTSK | P43235 | 4/20 | 0.52 |
| ▸ | CTSS | P25774 | 2/20 | 0.52 |
| ▸ | TACR1 | P25103 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7339599 | 0.89 | CYP1A2 (0.48) | CTSLCTSBCTSKCTSS | |
| SCHEMBL7343203 | 0.89 | CYP1A2 (0.48) | CTSLCTSBCTSKCTSS | |
| SCHEMBL7337274 | 0.79 | PSMB1 (0.49) | CTSLCTSBCTSKCTSS | |
| SCHEMBL8399106 | 0.77 | KDM1A (0.34) | — | |
| SCHEMBL7337127 | 0.77 | CTSL (0.53) | CTSLCTSBCTSKCTSSTACR1 | |
| SCHEMBL7337140 | 0.77 | CTSL (0.53) | CTSLCTSBCTSKCTSSTACR1 | |
| SCHEMBL10802556 | 0.76 | CTSL (0.70) | CTSLCTSBCTSKCTSSTACR1 | |
| SCHEMBL19807564 | 0.76 | TACR1 (0.72) | CTSLCTSBCTSKCTSSTACR1 | |
| SCHEMBL7275434 | 0.74 | ECE1 (0.65) | CTSLCTSBCTSKCTSSTACR1 | |
| SCHEMBL9088735 | 0.74 | CAPN1 (0.72) | CTSLCTSBCTSKCTSSTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5416117-A | Protease inhibitor | MITSUBISHI KASEI CORPORATION (JP) | 1995-05-16 | — | — | US | disclosed |
| EP-0520427-B1 | Cyclopropenone derivatives | MITSUBISHI CHEM IND (JP) | 1994-12-14 | — | — | EP | disclosed |
| US-5328909-A | Protease inhibitors | MITSUBISHI KASEI CORPORATION (JP) | 1994-07-12 | — | — | US | disclosed |
| EP-0520427-A1 | Cyclopropenone derivatives | Mitsubishi Chemical Corporation (JP) | 1992-12-30 | — | — | EP | disclosed |