Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 3/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 3/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 2/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | CPA1 | P15085 | 1/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | NMT2 | O60551 | 1/20 | 0.34 |
| ▸ | NMT1 | P30419 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 3/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7347656 | 0.86 | CACNA1B (0.36) | RENCACNA1BMMP1MMP3MME | |
| SCHEMBL7339993 | 0.85 | CACNA1B (0.35) | RENCACNA1BPSMB5USP30 | |
| SCHEMBL7348064 | 0.84 | CTSL (0.42) | RENCACNA1BMMP1MMP2MMP3 | |
| SCHEMBL7347209 | 0.84 | FFAR1 (0.41) | RENCACNA1BPSMB5 | |
| SCHEMBL7344635 | 0.84 | MMP1 (0.36) | CACNA1BMMP1MMP2MMP3 | |
| SCHEMBL7337630 | 0.81 | LMNA (0.36) | CACNA1BMMP1MMP2MMP3MME | |
| SCHEMBL7343130 | 0.81 | CTSL (0.42) | RENCACNA1BMMP1MMP2MMP3 | |
| SCHEMBL7337467 | 0.80 | CACNA1B (0.47) | RENCACNA1BMMP1MMP2MMP3 | |
| SCHEMBL7340724 | 0.79 | PPARG (0.43) | CACNA1BMMP1 | |
| SCHEMBL7348620 | 0.79 | NOS2 (0.37) | CACNA1BMMP1MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | claimed |
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |