Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 5/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | GRB2 | P62993 | 2/20 | 0.31 |
| ▸ | MC4R | P32245 | 2/20 | 0.30 |
| ▸ | MC5R | P33032 | 2/20 | 0.30 |
| ▸ | MC3R | P41968 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7347656 | 0.85 | CACNA1B (0.36) | MMP1CACNA1BMMP3 | |
| SCHEMBL7348620 | 0.84 | NOS2 (0.37) | MMP1CACNA1BMMP2MMP3 | |
| SCHEMBL7337462 | 0.84 | REN (0.38) | MMP1CACNA1BMMP2MMP3 | |
| SCHEMBL7345788 | 0.83 | ALDH1A1 (0.42) | MMP1CACNA1BMMP2MMP3 | |
| SCHEMBL7348064 | 0.83 | CTSL (0.42) | MMP1CACNA1BMMP2MMP3 | |
| SCHEMBL7337630 | 0.80 | LMNA (0.36) | MMP1CACNA1BMMP2MMP3 | |
| SCHEMBL7344639 | 0.80 | CACNA1B (0.45) | MMP1CACNA1BMMP2MMP3 | |
| SCHEMBL7343130 | 0.79 | CTSL (0.42) | MMP1CACNA1BMMP2MMP3 | |
| SCHEMBL7339993 | 0.78 | CACNA1B (0.35) | CACNA1BMC4RMC5RMC3R | |
| SCHEMBL7340724 | 0.78 | PPARG (0.43) | MMP1CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | claimed |
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |