Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 6/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7330585 | 0.93 | ALDH1A1 (0.53) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL7337815 | 0.82 | IDO1 (0.45) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL7333438 | 0.77 | ALDH1A1 (0.50) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL7338080 | 0.77 | DCTPP1 (0.42) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL7335512 | 0.72 | DCTPP1 (0.43) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL7337801 | 0.71 | DCTPP1 (0.40) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL7337608 | 0.68 | RAB9A (0.43) | KDM4EALDH1A1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL7330788 | 0.68 | NPC1 (0.42) | KDM4ESMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL1952256 | 0.65 | PLA2G4A (0.52) | SMN1; SMN2FAAH | |
| SCHEMBL7897455 | 0.65 | DCTPP1 (0.46) | KDM4EALDH1A1HPGDSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191124-B1 | VIRICIDES | PHARMACIA & UPJOHN COMPANY | 2001-02-20 | — | — | US | claimed |
| EP-0757692-A1 | METHANOL DERIVATIVES FOR TREATMENT OF RETROVIRAL INFECTIONS ESPECIALLY HIV INFECTIONS | PHARMACIA & UPJOHN COMPANY (US) | 1997-02-12 | — | — | EP | claimed |
| WO-1995029922-A1 | METHANOL DERIVATIVES FOR TREATMENT OF RETROVIRAL INFECTIONS ESPECIALLY HIV INFECTIONS | PHARMACIA & UPJOHN COMPANY (US) | 1995-11-09 | — | — | WO | claimed |
| US-6191124-B1 | VIRICIDES | PHARMACIA & UPJOHN COMPANY | 2001-02-20 | — | — | US | disclosed |
| EP-0757692-A1 | METHANOL DERIVATIVES FOR TREATMENT OF RETROVIRAL INFECTIONS ESPECIALLY HIV INFECTIONS | PHARMACIA & UPJOHN COMPANY (US) | 1997-02-12 | — | — | EP | disclosed |
| WO-1995029922-A1 | METHANOL DERIVATIVES FOR TREATMENT OF RETROVIRAL INFECTIONS ESPECIALLY HIV INFECTIONS | PHARMACIA & UPJOHN COMPANY (US) | 1995-11-09 | — | — | WO | disclosed |