Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7347613 | 0.93 | CTSK (0.33) | ACEMEN1KMT2A | |
| SCHEMBL7340132 | 0.83 | ACE (0.32) | ACEOPRM1 | |
| SCHEMBL7341358 | 0.78 | AKR1C1 (0.38) | OPRM1MEN1KMT2A | |
| SCHEMBL7342000 | 0.78 | HDAC3 (0.38) | — | |
| SCHEMBL7339039 | 0.78 | — | — | |
| SCHEMBL7342749 | 0.77 | CTSK (0.33) | ACE | |
| SCHEMBL14343367 | 0.76 | P4HB (0.32) | OPRM1 | |
| SCHEMBL11235013 | 0.73 | LMNA (0.34) | ACEOPRM1KMT2A | |
| SCHEMBL7338878 | 0.71 | DDB1 (0.37) | MEN1KMT2A | |
| SCHEMBL7313309 | 0.71 | FFAR4 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4316906-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1982-02-23 | — | — | US | disclosed |