SCHEMBL734012

SCHEMBL734012

CCOC(OCC)O[SiH2]CC(C)CCl

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.39
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL375872 0.82 THRB (0.40) THRBLMNA
SCHEMBL2552956 0.82 THRB (0.40) THRBLMNA
SCHEMBL56349 0.76 THRB (0.48) THRBLMNA
SCHEMBL15735992 0.73 THRB (0.32) THRB
SCHEMBL56737 0.72 THRB (0.43) THRBLMNA
SCHEMBL734469 0.71 LMNA (0.35) THRBLMNA
SCHEMBL29289473 0.71 THRB (0.53) THRBLMNA
SCHEMBL6064040 0.71 THRB (0.53) THRBLMNA
SCHEMBL55867 0.69 THRB (0.40) THRB
SCHEMBL15733711 0.68 THRB (0.34) THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8138365-B2 Method for producing organosilanes EVONIK DEGUSSA GMBH (DE) 2012-03-20 US claimed
US-20100217026-A1 Method for producing organosilanes EVONIK OPERATIONS GMBH (DE) 2010-08-26 US claimed
EP-2057172-B1 METHOD FOR PRODUCING ORGANOSILANES EVONIK DEGUSSA GMBH (DE) 2013-09-11 EP disclosed
US-8138365-B2 Method for producing organosilanes EVONIK DEGUSSA GMBH (DE) 2012-03-20 US disclosed
US-20100217026-A1 Method for producing organosilanes EVONIK OPERATIONS GMBH (DE) 2010-08-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100217026-A1 Method for producing organosilanes TST, STS, HAO2 THRB 2259/4885LMNA 4751/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.