SCHEMBL56737

SCHEMBL56737

CCOC(OCC)O[SiH2]CCCl

nearest known ligand 0.43

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.43
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL55867 0.87 THRB (0.40) THRB
SCHEMBL6064040 0.85 THRB (0.53) THRBLMNA
SCHEMBL31187718 0.81 THRB (0.48) THRBLMNA
SCHEMBL6064088 0.81 THRB (0.48) THRBLMNA
SCHEMBL56349 0.81 THRB (0.48) THRBLMNA
Hydrochloric Acid SCHEMBL11276200 0.78 LMNA (0.44) LMNA
SCHEMBL375781 0.77 THRB (0.43) THRBLMNA
SCHEMBL29289476 0.77 THRB (0.43) THRBLMNA
SCHEMBL2552782 0.77 THRB (0.43) THRBLMNA
SCHEMBL56524 0.77 THRB (0.39) THRBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8138365-B2 Method for producing organosilanes EVONIK DEGUSSA GMBH (DE) 2012-03-20 US claimed
US-20100217026-A1 Method for producing organosilanes EVONIK OPERATIONS GMBH (DE) 2010-08-26 US claimed
US-12600735-B2 Method for producing polysulphane-silanes by means of phase transfer catalysis EVONIK OPERATIONS GMBH (DE) 2026-04-14 US disclosed
US-12540146-B2 Process for the production of sulfur containing silanes by utilization of phase transfer catalysis EVONIK OPERATIONS GMBH (DE) 2026-02-03 US disclosed
CN-113366003-B Method for preparing polysulfane silanes by phase transfer catalysis 赢创运营有限公司 2025-02-11 CN disclosed
CN-113214308-B Method for producing polysulfide silanes 赢创运营有限公司 2024-12-31 CN disclosed
CN-113597427-B Method for producing sulfur-containing silanes using phase transfer catalysis 赢创运营有限公司 2024-09-17 CN disclosed
EP-3862359-B1 METHOD FOR PRODUCING POLYSULFANE SILANES EVONIK OPERATIONS GMBH (DE) 2024-04-03 EP disclosed
EP-4100414-B1 A PROCESS FOR THE PRODUCTION OF SULFUR CONTAINING SILANES BY UTILIZATION OF PHASE TRANSFER CATALYSIS EVONIK OPERATIONS GMBH (DE) 2023-10-11 EP disclosed
US-20230265113-A1 PROCESS FOR PREPARING POLYSULFANE SILANES BY MEANS OF PHASE TRANSFER CATALYSIS EVONIK OPERATIONS GMBH (DE) 2023-08-24 US disclosed
EP-4208469-A1 PROCESS FOR PREPARING POLYSULFANE SILANES BY MEANS OF PHASE TRANSFER CATALYSIS Evonik Operations GmbH (DE) 2023-07-12 EP disclosed
EP-1529782-B1 Process for preparing mercaptoorganyl alkoxy silanes DEGUSSA (DE) 2006-05-10 EP disclosed
US-7019160-B2 Process for the preparation of (mercaptoorganyl)alkoxysilanes DEGUSSA AG (DE) 2006-03-28 US disclosed
EP-1538152-B1 Process for the preparation of (mercaptoorganyl)-alkoxysilanen DEGUSSA (DE) 2006-03-22 EP disclosed
US-6995280-B2 Process for preparing (mercaptoorganyl)alkoxysilanes DEGUSSA AG (DE) 2006-02-07 US disclosed
US-20050124822-A1 Process for the preparation of (mercaptoorganyl)alkoxysilanes EVONIK OPERATIONS GMBH (DE) 2005-06-09 US disclosed
US-20050124821-A1 Process for preparing (mercaptoorganyl)alkoxysilanes EVONIK OPERATIONS GMBH (DE) 2005-06-09 US disclosed
EP-1538152-A1 Process for the preparation of (mercaptoorganyl)-alkoxysilanen Degussa AG (DE) 2005-06-08 EP disclosed
EP-1529782-A1 Process for preparing mercaptoorganyl alkoxy silanes Degussa AG (DE) 2005-05-11 EP disclosed
US-4332612-A N-METHYL-2-PYRROLIDONE AND A HALOALKYL SILANE GAF CORPORATION (US) 1982-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230265113-A1 PROCESS FOR PREPARING POLYSULFANE SILANES BY MEANS OF PHASE TRANSFER CATALYSIS MRPS22, MRPS23, SRM THRB 2082/4885LMNA 3783/4885
US-20050124821-A1 Process for preparing (mercaptoorganyl)alkoxysilanes ADH1C, ADH1A, MPST THRB 4696/4885LMNA 3513/4885
US-20100217026-A1 Method for producing organosilanes TST, STS, HAO2 THRB 2259/4885LMNA 4751/4885
US-12600735-B2 Method for producing polysulphane-silanes by means of phase transfer catalysis MSR1, AS3MT, RRM1 THRB 1860/4885LMNA 1808/4885
US-20050124822-A1 Process for the preparation of (mercaptoorganyl)alkoxysilanes MPST, ADH1A, ADH1C THRB 4640/4885LMNA 4012/4885
US-12540146-B2 Process for the production of sulfur containing silanes by utilization of phase transfer catalysis TST, SFN, SAMM50 THRB 1842/4885LMNA 3503/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.