Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | GSK3B | P49841 | 3/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7342306 | 0.82 | MEN1 (0.56) | ALDH1A1TSHRKDM4ESMN1; SMN2LTB4R2 | |
| SCHEMBL7340750 | 0.81 | MEN1 (0.45) | HDAC1HDAC8HDAC6ALDH1A1TSHR | |
| SCHEMBL7340748 | 0.80 | HDAC1 (0.51) | HDAC1HDAC8HDAC6ALDH1A1TSHR | |
| SCHEMBL7340970 | 0.80 | CNR2 (0.56) | HDAC1HDAC8HDAC6ALDH1A1TSHR | |
| SCHEMBL7342337 | 0.80 | MEN1 (0.44) | HDAC1HDAC8HDAC6ALDH1A1TSHR | |
| SCHEMBL7339673 | 0.80 | LMNA (0.46) | HDAC1HDAC8HDAC6ALDH1A1TSHR | |
| SCHEMBL7338250 | 0.79 | TSPO (0.44) | ALDH1A1KDM4EGAAKMT2A | |
| SCHEMBL7341990 | 0.79 | ALDH1A1 (0.59) | HDAC1HDAC8HDAC6ALDH1A1TSHR | |
| SCHEMBL7346461 | 0.78 | OPRM1 (0.53) | ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7347840 | 0.72 | MAPT (0.50) | ALDH1A1TSHRKDM4ELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585500-A1 | Diaryl piperazineacetamides as antimuscarinic agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-03-09 | — | — | EP | disclosed |