Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7339673 | 0.81 | LMNA (0.46) | LMNAKMT2AALDH1A1MEN1HDAC6 | |
| SCHEMBL25190162 | 0.80 | TSPO (0.46) | LMNAKMT2AALDH1A1MEN1HDAC6 | |
| SCHEMBL7347657 | 0.79 | LMNA (0.49) | LMNAKMT2AALDH1A1POLBKDM4E | |
| SCHEMBL436539 | 0.78 | DRD4 (0.50) | LMNAKMT2AALDH1A1KDM4ETSHR | |
| SCHEMBL7348711 | 0.78 | HDAC6 (0.45) | KMT2ATLR7MEN1HDAC6 | |
| SCHEMBL7341561 | 0.78 | RNF4 (0.46) | LMNAKMT2AALDH1A1MEN1HDAC6 | |
| SCHEMBL25259732 | 0.77 | TSPO (0.54) | LMNAALDH1A1SIGMAR1KDM4ETSHR | |
| SCHEMBL7339537 | 0.75 | CACNA2D1 (0.56) | LMNAKMT2AALDH1A1KDM4ETSHR | |
| SCHEMBL9660120 | 0.74 | KMT2A (0.55) | LMNAKMT2AALDH1A1MEN1HDAC6 | |
| SCHEMBL4490990 | 0.74 | DRD4 (0.46) | LMNASIGMAR1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585500-A1 | Diaryl piperazineacetamides as antimuscarinic agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-03-09 | — | — | EP | disclosed |