Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | HTR2B | P41595 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7384746 | 0.81 | ALDH1A1 (0.51) | RAB9ASMN1; SMN2GPR84CASP3SENP7 | |
| SCHEMBL29699123 | 0.76 | SRD5A2 (0.50) | RAB9ASMN1; SMN2GPR84CASP3SENP7 | |
| SCHEMBL9986249 | 0.75 | HTR2C (0.49) | RAB9ASMN1; SMN2GPR84CASP3SENP7 | |
| SCHEMBL9986247 | 0.75 | SRD5A2 (0.45) | RAB9ASMN1; SMN2GPR84CASP3SENP7 | |
| SCHEMBL5048243 | 0.75 | TSHR (0.54) | RAB9ASMN1; SMN2GPR84SRD5A2FAAH | |
| SCHEMBL27426495 | 0.73 | SRD5A2 (0.57) | RAB9ASMN1; SMN2GPR84SRD5A2FAAH | |
| SCHEMBL6370589 | 0.73 | GPR84 (0.44) | RAB9ASMN1; SMN2GPR84CASP3SENP7 | |
| SCHEMBL7342269 | 0.72 | ALDH1A1 (0.51) | RAB9ASMN1; SMN2GPR84CASP3SENP7 | |
| SCHEMBL3230081 | 0.72 | ALDH1A1 (0.46) | RAB9ASMN1; SMN2GPR84SRD5A2FAAH | |
| SCHEMBL1903357 | 0.72 | TSHR (0.48) | RAB9ASMN1; SMN2GPR84CASP3SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112846-A | Nonsteroidal antiinflammatory agents | WARNER-LAMBERT COMPANY (US) | 1992-05-12 | — | — | US | disclosed |
| US-5075330-A | N-hydroxyamide, N-hydroxythioamide, N-hydroxyurea, and N-hydroxythiourea derivatives of selected NSAIDS as antiinflammatory agents | WARNER-LAMBERT CO. (US) | 1991-12-24 | — | — | US | disclosed |
| US-4981865-A | N-hydroxyamide, N-hydroxythioamide, hydroxyurea, and N-hydroxythiourea derivatives of selected nsaids as antiinflammatory agents | WARNER-LAMBERT CO. (US) | 1991-01-01 | — | — | US | disclosed |