Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20621602 | 0.84 | MAPT (0.43) | RAB9ANPC1SMN1; SMN2MAPK1CYP1A2 | |
| SCHEMBL1527717 | 0.79 | PNMT (0.45) | RAB9ANPC1SMN1; SMN2HTR2BALDH1A1 | |
| Fluorene SCHEMBL23748026 | 0.78 | MAOA (0.42) | SRD5A2RAB9ANPC1MAPK1HTR2C | |
| SCHEMBL142445 | 0.78 | ALDH1A1 (0.47) | RAB9ANPC1MAPK1SLC6A2ALDH1A1 | |
| SCHEMBL11323517 | 0.78 | ALDH1A1 (0.47) | RAB9ANPC1MAPK1SLC6A2ALDH1A1 | |
| SCHEMBL7384746 | 0.77 | ALDH1A1 (0.51) | GPR84FAAHSRD5A2RAB9ATSHR | |
| Fluorene SCHEMBL27844771 | 0.77 | MAOA (0.44) | SRD5A2RAB9ANPC1MAPK1HTR2C | |
| SCHEMBL1279658 | 0.76 | ALDH1A1 (0.46) | RAB9ANPC1MAPK1SLC6A2ALDH1A1 | |
| Carbamic Acid SCHEMBL28871401 | 0.74 | CYP2C19 (0.44) | RAB9ANPC1SMN1; SMN2MAPK1SLC6A2 | |
| SCHEMBL17103886 | 0.74 | MMP1 (0.49) | TSHRMAOAHTTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025032254-A1 | ANTHRACYCLINE DERIVATIVES AND CONJUGATES AND USES THEREOF | ASTRAZENECA AB (SE) | 2025-02-13 | — | — | WO | disclosed |
| US-6858396-B2 | Positively charged non-natural amino acids, methods of making and using thereof in peptides | MEDICAL UNIVERSITY OF SOUTH CAROLINA (US) | 2005-02-22 | — | — | US | disclosed |
| US-6783946-B2 | CLOSELY REPLICATE THE NATURAL AMINO ACIDS LYSINE AND ARGININE. | MEDICAL UNIVERSITY OF SOUTH CAROLINA | 2004-08-31 | — | — | US | disclosed |
| EP-1366017-A2 | NON-NATURAL BASIC AMINO ACIDS, THEIR PREPARATION AND USE | MUSC Foundation For Research Development (US) | 2003-12-03 | — | — | EP | disclosed |
| US-6566330-B1 | As chemical intermediate | MEDICAL UNIVERSITY OF SOUTH CAROLINA FOUNDATION RESEARCH DEVELOPMENT | 2003-05-20 | — | — | US | disclosed |
| EP-1303485-A1 | PYRROLIDINE DERIVATIVES AS INHIBITORS OF ENDOTHELIN-CONVERTING ENZYME | F. HOFFMANN-LA ROCHE AG (CH) | 2003-04-23 | — | — | EP | disclosed |
| US-6541638-B2 | (2S,4S)-1-(4-Mercapto-1-(naphthalene-2-sulfonyl)-pyrrolidine-2 -carbonyl)-piperidine-4-carboxylic acid ethyl ester for example; zinc protease inhibitors; for treating diseases associated with vasoconstriction | HOFFMAN-LA ROCHE INC. | 2003-04-01 | — | — | US | disclosed |
| EP-0998280-A4 | CARBOHYDRATE SCAFFOLD COMPOUNDS AND LIBRARIES | INCARA PHARMACEUTICALS CORP (US) | 2002-11-06 | — | — | EP | disclosed |
| US-20020137730-A1 | Positively charged non-natural amino acids, methods of making and using thereof in peptides | MEDICAL UNIVERSITY OF SOUTH CAROLINA | 2002-09-26 | — | — | US | disclosed |
| US-20020068701-A1 | Positively charged non-natural amino acids, methods of making thereof, and use thereof in peptides | MEDICAL UNIVERSITY OF SOUTH CAROLINA | 2002-06-06 | — | — | US | disclosed |
| US-20020049243-A1 | Pyrrolidine derivatives | HOFFMANN-LA ROCHE INC. | 2002-04-25 | — | — | US | disclosed |
| WO-2002022553-A2 | NON-NATURAL BASIC AMINO ACIDS, THEIR PREPARATION AND USE | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2002-03-21 | — | — | WO | disclosed |
| US-6358922-B1 | ARGININE DERIVATIVES | MEDICAL UNIVERSITY OF SOUTH CAROLINA | 2002-03-19 | — | — | US | disclosed |
| WO-2002006222-A1 | PYRROLIDINE DERIVATIVES AS INHIBITORS OF ENDOTHELIN-CONVERTING ENZYME | F. HOFFMANN-LA ROCHE AG (CH) | 2002-01-24 | — | — | WO | disclosed |
| EP-0998280-A1 | CARBOHYDRATE SCAFFOLD COMPOUNDS AND LIBRARIES | Incara Pharmaceuticals Corp. (US) | 2000-05-10 | — | — | EP | disclosed |
| US-6043218-A | Positively charged non-natural amino acids, methods of making thereof, and use thereof in peptides | MEDICAL UNIVERSITY OF SOUTH CAROLINA (US) | 2000-03-28 | — | — | US | disclosed |
| WO-1998053813-A1 | CARBOHYDRATE SCAFFOLD COMPOUNDS AND LIBRARIES | INCARA PHARMACEUTICALS CORP. (US) | 1998-12-03 | — | — | WO | disclosed |
| WO-1998017626-A2 | POSITIVELY CHARGED NON-NATURAL AMINO ACIDS, METHODS OF MAKING THEREOF, AND USE THEREOF IN PEPTIDES | MEDICAL UNIVERSITY OF SOUTH CAROLINA (US) | 1998-04-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020068701-A1 | Positively charged non-natural amino acids, methods of making thereof, and use thereof in peptides | ARGLU1, NGLY1, QPCTL | GPR84 1087/4885FAAH 3750/4885SRD5A2 4768/4885 |
| US-20020137730-A1 | Positively charged non-natural amino acids, methods of making and using thereof in peptides | NGLY1, LNPEP, DNPEP | GPR84 1776/4885FAAH 4299/4885SRD5A2 4814/4885 |
| US-20020049243-A1 | Pyrrolidine derivatives | PREP, PEPD, DNPEP | GPR84 3306/4885FAAH 559/4885SRD5A2 1101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.