Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | RORC | P51449 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7350727 | 0.90 | NR3C1 (0.46) | ALDH1A1TSHRRORCMAPTNR3C1 | |
| SCHEMBL7351410 | 0.88 | THRA (0.47) | ALDH1A1THRBTHRAHSP90AB1 | |
| SCHEMBL7348710 | 0.85 | ALDH1A1 (0.41) | ALDH1A1TSHRRORCMAPTHDAC1 | |
| SCHEMBL7348911 | 0.84 | SIGMAR1 (0.39) | ALDH1A1TSHRABL1RIN1HDAC1 | |
| SCHEMBL7351856 | 0.80 | RORC (0.38) | ALDH1A1TSHRRORCMAPTNR3C1 | |
| SCHEMBL7351863 | 0.80 | KMT2A (0.41) | ALDH1A1TSHRRORCMAPTKDM4E | |
| SCHEMBL7351859 | 0.79 | ALDH1A1 (0.38) | ALDH1A1TSHRRORCMAPTNR3C1 | |
| SCHEMBL7352158 | 0.78 | ALDH1A1 (0.41) | ALDH1A1TSHRRORCMAPTNR3C1 | |
| SCHEMBL7346441 | 0.78 | PTGDR2 (0.43) | ALDH1A1POLBPKMLMNASMN1; SMN2 | |
| SCHEMBL7346510 | 0.78 | KMT2A (0.37) | ALDH1A1TSHRRORCMAPTHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5284971-A | No cardiac side effects | SYNTEX (U.S.A.) INC. (US) | 1994-02-08 | — | — | US | disclosed |