Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 8/20 | 0.45 |
| ▸ | THRA | P10827 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | RORC | P51449 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7343576 | 0.90 | ALDH1A1 (0.42) | NR3C1THRBTHRAALDH1A1TSHR | |
| SCHEMBL7352158 | 0.86 | ALDH1A1 (0.41) | NR3C1THRBTHRAALDH1A1TSHR | |
| SCHEMBL7256710 | 0.85 | THRB (0.59) | THRBTHRA | |
| SCHEMBL7256723 | 0.84 | CA5A (0.44) | NR3C1THRBTHRAALDH1A1TSHR | |
| SCHEMBL7348710 | 0.84 | ALDH1A1 (0.41) | THRBTHRAALDH1A1TSHRRORC | |
| SCHEMBL7351859 | 0.81 | ALDH1A1 (0.38) | NR3C1THRBTHRAALDH1A1TSHR | |
| SCHEMBL7351863 | 0.81 | KMT2A (0.41) | THRBTHRAALDH1A1TSHRRORC | |
| SCHEMBL7351856 | 0.81 | RORC (0.38) | NR3C1THRBTHRAALDH1A1TSHR | |
| SCHEMBL7256735 | 0.78 | PTGDR2 (0.47) | THRBTHRAALDH1A1TSHRCA5A | |
| SCHEMBL7351410 | 0.77 | THRA (0.47) | THRBTHRAALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5284971-A | No cardiac side effects | SYNTEX (U.S.A.) INC. (US) | 1994-02-08 | — | — | US | disclosed |