Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7350255 | 0.90 | TSHR (0.39) | MEN1KMT2ALMNATSHRBCHE | |
| SCHEMBL7346734 | 0.84 | MAPT (0.39) | TSHRALDH1A1 | |
| SCHEMBL7352882 | 0.77 | POLB (0.36) | MEN1KMT2ALMNATSHRALDH1A1 | |
| SCHEMBL7322208 | 0.72 | CA2 (0.33) | MEN1KMT2ANPSR1TSHR | |
| SCHEMBL7344165 | 0.71 | MEN1 (0.45) | MEN1KMT2ALMNATSHRALDH1A1 | |
| SCHEMBL11795231 | 0.71 | HTR1A (0.53) | HTR1ALMNATSHRBCHEALDH1A1 | |
| SCHEMBL362355 | 0.71 | CA2 (0.44) | MEN1KMT2ANPSR1TSHRALDH1A1 | |
| SCHEMBL7349941 | 0.70 | KMT2A (0.47) | MEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL7331788 | 0.69 | CA2 (0.33) | MEN1KMT2ANPSR1TSHR | |
| SCHEMBL7331335 | 0.69 | KMT2A (0.48) | MEN1KMT2ALMNATP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4892885-A | CARDIOTONICS, DIURETICS | AMERICAN CYANAMID COMPANY | 1990-01-09 | — | — | US | disclosed |