Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | VEGFA | P15692 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7344165 | 0.99 | MEN1 (0.45) | KMT2AMEN1ALDH1A1CHRNA7GAA | |
| SCHEMBL7352882 | 0.75 | POLB (0.36) | KMT2AMEN1ALDH1A1TSHRKDM4E | |
| SCHEMBL7346734 | 0.73 | MAPT (0.39) | ALDH1A1GAATSHR | |
| SCHEMBL7350255 | 0.71 | TSHR (0.39) | KMT2AMEN1ALDH1A1GAAHTT | |
| SCHEMBL7344848 | 0.70 | RORC (0.39) | KMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL753109 | 0.69 | KMT2A (0.57) | KMT2AMEN1ALDH1A1CHRNA7KDM4E | |
| SCHEMBL11361974 | 0.69 | ALDH1A1 (0.65) | KMT2AMEN1ALDH1A1CHRNA7HTT | |
| SCHEMBL11194277 | 0.69 | ALDH1A1 (0.73) | KMT2AMEN1ALDH1A1CHRNA7HTT | |
| SCHEMBL362355 | 0.69 | CA2 (0.44) | KMT2AMEN1ALDH1A1GAATSHR | |
| SCHEMBL7433040 | 0.67 | ALDH1A1 (0.67) | KMT2AMEN1ALDH1A1CHRNA7HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4892885-A | CARDIOTONICS, DIURETICS | AMERICAN CYANAMID COMPANY | 1990-01-09 | — | — | US | disclosed |