Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 5/20 | 0.37 |
| ▸ | ACHE | P22303 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7344848 | 0.90 | RORC (0.39) | TSHRMEN1KMT2ABCHELMNA | |
| SCHEMBL7346734 | 0.85 | MAPT (0.39) | TSHRGAAMAPTALDH1A1 | |
| SCHEMBL7352882 | 0.78 | POLB (0.36) | TSHRMEN1KMT2ALMNAMAPT | |
| SCHEMBL7322208 | 0.73 | CA2 (0.33) | TSHRMEN1KMT2AMAPT | |
| SCHEMBL7344165 | 0.72 | MEN1 (0.45) | TSHRMEN1GAAHTTKMT2A | |
| SCHEMBL362355 | 0.72 | CA2 (0.44) | TSHRMEN1GAAKMT2ACYP2D6 | |
| SCHEMBL7349941 | 0.71 | KMT2A (0.47) | TSHRMEN1GAAHTTKMT2A | |
| SCHEMBL7331788 | 0.70 | CA2 (0.33) | TSHRMEN1KMT2AMAPT | |
| SCHEMBL17099130 | 0.70 | NPSR1 (0.49) | TSHRMEN1GAAKMT2AALDH1A1 | |
| SCHEMBL7331335 | 0.70 | KMT2A (0.48) | TSHRMEN1HTTKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4892885-A | CARDIOTONICS, DIURETICS | AMERICAN CYANAMID COMPANY | 1990-01-09 | — | — | US | disclosed |