Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | G6PD | P11413 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CCR6 | P51684 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7346734 | 0.81 | MAPT (0.39) | SLC6A2SLC6A3SLC6A4ALDH1A1MAPT | |
| SCHEMBL7350255 | 0.78 | TSHR (0.39) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7344848 | 0.77 | RORC (0.39) | LMNAALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL7344165 | 0.76 | MEN1 (0.45) | POLBLMNAALDH1A1KDM4EMEN1 | |
| SCHEMBL7349941 | 0.75 | KMT2A (0.47) | POLBALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL7343029 | 0.74 | LMNA (0.43) | POLBLMNASLC6A2SLC6A3SLC6A4 | |
| SCHEMBL7322208 | 0.74 | CA2 (0.33) | POLBMAPTKDM4EHPGDMEN1 | |
| SCHEMBL362355 | 0.73 | CA2 (0.44) | POLBALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7331788 | 0.71 | CA2 (0.33) | POLBMAPTKDM4EHPGDMEN1 | |
| SCHEMBL7331335 | 0.71 | KMT2A (0.48) | POLBSMN1; SMN2LMNAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4892885-A | CARDIOTONICS, DIURETICS | AMERICAN CYANAMID COMPANY | 1990-01-09 | — | — | US | disclosed |