Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7350255 | 0.85 | TSHR (0.39) | MAPTALDH1A1TSHRGAA | |
| SCHEMBL7344848 | 0.84 | RORC (0.39) | ALDH1A1TSHR | |
| SCHEMBL7352882 | 0.81 | POLB (0.36) | MAPTSLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL7322208 | 0.76 | CA2 (0.33) | MAPTTSHRUSP2 | |
| SCHEMBL7344165 | 0.74 | MEN1 (0.45) | ALDH1A1TSHRGAA | |
| SCHEMBL362355 | 0.74 | CA2 (0.44) | MAPTALDH1A1TSHRUSP2GAA | |
| SCHEMBL7349941 | 0.73 | KMT2A (0.47) | ALDH1A1TSHRGAA | |
| SCHEMBL7331788 | 0.72 | CA2 (0.33) | MAPTTSHRUSP2 | |
| SCHEMBL17099130 | 0.72 | NPSR1 (0.49) | ALDH1A1TSHRGAA | |
| SCHEMBL7331335 | 0.72 | KMT2A (0.48) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4892885-A | CARDIOTONICS, DIURETICS | AMERICAN CYANAMID COMPANY | 1990-01-09 | — | — | US | disclosed |