Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.37 |
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7347489 | 0.88 | HTR1A (0.38) | HTR1ASIGMAR1DRD2DRD3LMNA | |
| SCHEMBL7352340 | 0.87 | HTR1A (0.42) | HTR1ASIGMAR1DRD2LMNASLC6A4 | |
| SCHEMBL7349099 | 0.85 | HTR1A (0.39) | HTR1ASIGMAR1DRD2DRD3LMNA | |
| SCHEMBL7350207 | 0.84 | SIGMAR1 (0.34) | HTR1ASIGMAR1DRD2DRD3LMNA | |
| SCHEMBL7354111 | 0.80 | HTR1A (0.56) | HTR1ASIGMAR1DRD2DRD3LMNA | |
| SCHEMBL7348281 | 0.79 | SIGMAR1 (0.34) | HTR1ASIGMAR1DRD2DRD3LMNA | |
| SCHEMBL7345096 | 0.78 | PER2 (0.38) | HTR1ADRD2DRD3 | |
| SCHEMBL7349930 | 0.75 | HTR1A (0.33) | HTR1ADRD2SLC6A4 | |
| SCHEMBL7347075 | 0.74 | P2RX7 (0.37) | HTR1A | |
| SCHEMBL7346162 | 0.72 | HTR1A (0.38) | HTR1ASIGMAR1DRD2DRD3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | claimed |
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | disclosed |