Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.62 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.56 |
| ▸ | HTR1A | P08908 | 4/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.55 |
| ▸ | DRD3 | P35462 | 3/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.55 |
| ▸ | DRD1 | P21728 | 2/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17204206 | 0.92 | DRD2 (0.70) | DRD2SIGMAR1HTR1AADRA2ASLC6A4 | |
| SCHEMBL7350313 | 0.85 | ALDH1A1 (0.68) | DRD2SIGMAR1HTR1AADRA2AADRA1A | |
| SCHEMBL7354269 | 0.84 | DRD2 (0.63) | DRD2SIGMAR1HTR1AADRA2ASLC6A4 | |
| SCHEMBL11755100 | 0.83 | ALDH1A1 (0.71) | SIGMAR1HTR1AADRA1ASLC6A3KCNH2 | |
| SCHEMBL7351979 | 0.79 | DRD2 (0.44) | DRD2SIGMAR1HTR1AADRA2ASLC6A4 | |
| SCHEMBL7350499 | 0.79 | DRD2 (0.44) | DRD2SIGMAR1HTR1AADRA2ASLC6A4 | |
| SCHEMBL11829198 | 0.78 | SIGMAR1 (0.64) | DRD2SIGMAR1HTR1AADRA2ASLC6A4 | |
| SCHEMBL12123771 | 0.78 | ALDH1A1 (0.73) | HTR1AKMT2A | |
| Hydrochloric Acid SCHEMBL11820622 | 0.77 | SIGMAR1 (0.62) | DRD2SIGMAR1HTR1AADRA2ASLC6A4 | |
| SCHEMBL9051774 | 0.77 | DRD2 (1.00) | DRD2SIGMAR1HTR1AADRA2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | claimed |
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | disclosed |