Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL6955401 | 0.88 | NLRP3 (0.44) | MAPK14NLRP3LMNAMAPTALDH1A1 | |
| SCHEMBL5047053 | 0.87 | LCK (0.40) | MAPK14NLRP3LMNAMAPTUSP2 | |
| SCHEMBL11663327 | 0.87 | MAPK14 (0.49) | MAPK14NLRP3MAPTALDH1A1L3MBTL1 | |
| SCHEMBL2104146 | 0.85 | MAPK14 (0.39) | CYP1A2MAPK14NLRP3LMNAMAPT | |
| SCHEMBL2865982 | 0.85 | MEN1 (0.41) | MAPK14MAPTALDH1A1HTTGAA | |
| SCHEMBL3786027 | 0.85 | ALDH1A1 (0.47) | MAPK14NLRP3LMNAMAPTMITF | |
| SCHEMBL24292090 | 0.83 | LCK (0.36) | MAPK14NLRP3LMNAUSP2ALDH1A1 | |
| SCHEMBL7534755 | 0.81 | MAPK14 (0.43) | CYP1A2CYP2A6MAPK14NLRP3POLB | |
| SCHEMBL11242607 | 0.79 | CYP1A2 (0.48) | CYP1A2CYP2A6LMNATSHRCYP2C19 | |
| SCHEMBL2100181 | 0.78 | TAS1R3 (0.36) | MAPK14NLRP3LMNAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4139308-B1 | PURINE DERIVATIVES AS DRUGS FOR THE TREATMENT OF NEONATAL HYPOXIA-ISCHEMIA BRAIN INJURY AND RELATED DISEASES | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2024-07-17 | — | — | EP | disclosed |
| CN-117510429-A | Compound containing methyl isoxazole structure, and preparation method and application thereof | 中国农业大学 | 2024-02-06 | — | — | CN | disclosed |
| WO-2024019957-A1 | COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | CELGENE CORPORATION (US) | 2024-01-25 | — | — | WO | disclosed |
| WO-2022266162-A1 | AZETIDINYL COMPOUNDS COMPRISING A CARBOXYLIC ACID GROUP FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | CELGENE CORPORATION (US) | 2022-12-22 | — | — | WO | disclosed |
| US-10993439-B2 | Mesoionic imidazopyridines as insecticides | BAYER AKTIENGESELLSCHAFT (DE) | 2021-05-04 | — | — | US | disclosed |
| US-20200146292-A1 | MESOIONIC IMIDAZOPYRIDINES AS INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-05-14 | — | — | US | disclosed |
| CN-103958487-A | Benzoic acid derivatives as eif4e inhibitors | HOFFMANN LA ROCHE | 2014-07-30 | — | — | CN | disclosed |
| US-7504391-B2 | Selective D1/D5 receptor antagonists for the treatment of obesity and CNS disorders | SCHERING CORPORATION (US) | 2009-03-17 | — | — | US | disclosed |
| US-20070293511-A1 | Crf Receptor Antagonists and Methods | SB PHARMCO PUERTO RICO INC. AND NEUROCRINE BIOSCIENCES, INC., A CORPORATION | 2007-12-20 | — | — | US | disclosed |
| US-4956346-A | URIDINE DERIVATIVES AS VIRICIDES | HOFFMANN-LA ROCHE INC. (US) | 1990-09-11 | — | — | US | disclosed |
| US-4886785-A | VIRICIDES, HERPES SIMPLEX | HOFFMANN-LA ROCHE INC. (US) | 1989-12-12 | — | — | US | disclosed |
| EP-0146271-A2 | Aralykyl (arylethynyl) aralkyl amines for use as vasodilators and antihypertensives | McNeilab, Inc. (US) | 1985-06-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10993439-B2 | Mesoionic imidazopyridines as insecticides | DDT, CHRM1, GRM1 | CYP1A2 660/4885CYP2A6 2898/4885MAPK14 4639/4885 |
| US-20070293511-A1 | Crf Receptor Antagonists and Methods | CRHR1, CRHR2, CRH | CYP1A2 977/4885CYP2A6 766/4885MAPK14 4717/4885 |
| US-20200146292-A1 | MESOIONIC IMIDAZOPYRIDINES AS INSECTICIDES | DDT, CHRM1, GRM1 | CYP1A2 660/4885CYP2A6 2898/4885MAPK14 4639/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.