Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 13/20 | 0.45 |
| ▸ | HTR2B | P41595 | 3/20 | 0.45 |
| ▸ | PPARG | P37231 | 3/20 | 0.44 |
| ▸ | PPARA | Q07869 | 3/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7360194 | 0.93 | MAPT (0.43) | P2RY14LMNASMN1; SMN2 | |
| SCHEMBL7351996 | 0.93 | ALDH1A1 (0.42) | PARP1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7360641 | 0.91 | PARP1 (0.42) | MCHR1PPARGPPARAPARP1P2RY14 | |
| SCHEMBL7357135 | 0.91 | KDM4E (0.42) | PPARGPPARAP2RY14SMN1; SMN2 | |
| SCHEMBL7351818 | 0.89 | ALDH1A1 (0.45) | PPARGPPARAPARP1LMNASMN1; SMN2 | |
| SCHEMBL7355377 | 0.88 | SMN1; SMN2 (0.44) | MCHR1LMNAHTTSMN1; SMN2 | |
| SCHEMBL7360674 | 0.87 | CYP2C19 (0.42) | PARP1LMNASMN1; SMN2 | |
| SCHEMBL7354615 | 0.85 | NOTUM (0.44) | PARP1SMN1; SMN2 | |
| SCHEMBL7354626 | 0.85 | KDM4E (0.43) | PARP1LMNASMN1; SMN2 | |
| SCHEMBL7360192 | 0.84 | KDM4E (0.42) | PARP1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995003298-A1 | BENZIMIDAZOLE DERIVATIVES USEFUL AS DOPAMINE RECEPTOR ANTAGONIST, 5-HT RECEPTOR AGONIST OR α1 RECEPTOR ANTAGONIST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-02 | — | — | WO | disclosed |