Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.33 |
| ▸ | GLA | P06280 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10446468 | 0.80 | KDM4E (0.33) | MAPT | |
| SCHEMBL9469517 | 0.77 | PKM (0.38) | PKMKMT2AAKR1B1HSD11B1L3MBTL1 | |
| SCHEMBL3968948 | 0.76 | KDM4E (0.33) | MAPT | |
| SCHEMBL9513409 | 0.73 | PKM (0.38) | PKMKMT2AAKR1B1HSD11B1TSHR | |
| SCHEMBL10717219 | 0.69 | SMN1; SMN2 (0.35) | KMT2AGLACES2CES1TSHR | |
| SCHEMBL27768567 | 0.68 | TSHR (0.34) | KMT2AGLACES2CES1L3MBTL1 | |
| SCHEMBL444646 | 0.67 | FFAR3 (0.35) | — | |
| SCHEMBL1847048 | 0.67 | PKM (0.37) | PKMKMT2AAKR1B1HSD11B1TSHR | |
| SCHEMBL14361783 | 0.67 | MMP2 (0.38) | KMT2AMAPTGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL14361686 | 0.65 | NOS2 (0.39) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11623928-B2 | Compositions, uses and methods for making them | Pimera, Inc. (US) | 2023-04-11 | — | — | US | disclosed |
| US-11618752-B2 | Compositions, uses and methods for making them | Pimera, Inc. (US) | 2023-04-04 | — | — | US | disclosed |
| US-20210094952-A1 | NOVEL COMPOSITIONS, USES AND METHODS FOR MAKING THEM | UNITED STATES GOVERNMENT | 2021-04-01 | — | — | US | disclosed |
| CN-111979770-A | Viloft fiber and apocynum venetum fiber blended fabric | 智科通用技术研究(广州)有限公司 | 2020-11-24 | — | — | CN | disclosed |
| CN-111979759-A | Anti-mite home textile fabric | 智科通用技术研究(广州)有限公司 | 2020-11-24 | — | — | CN | disclosed |
| US-20200361937-A1 | NOVEL COMPOSITIONS, USES AND METHODS FOR MAKING THEM | UNITED STATES GOVERNMENT | 2020-11-19 | — | — | US | disclosed |
| CN-111910429-A | Mite removing agent for spinning | 智科通用技术研究(广州)有限公司 | 2020-11-10 | — | — | CN | disclosed |
| US-10745403-B2 | Compositions, uses and methods for making them | Pimera, Inc. (US) | 2020-08-18 | — | — | US | disclosed |
| US-10590134-B2 | Compositions, uses and methods for making them | Pimera, Inc. (US) | 2020-03-17 | — | — | US | disclosed |
| US-10442801-B2 | Compositions, uses and methods for making them | Pimera, Inc. (US) | 2019-10-15 | — | — | US | disclosed |
| EP-3140305-A1 | NOVEL COMPOSITIONS, USES AND METHODS FOR MAKING THEM | Pimera, Inc. (US) | 2017-03-15 | — | — | EP | disclosed |
| US-9512123-B2 | Compositions, uses and methods for making them | Pimera, Inc. (US) | 2016-12-06 | — | — | US | disclosed |
| US-20160326176-A1 | Novel Compositions, Uses and Methods for Making Them | PIMERA, INC | 2016-11-10 | — | — | US | disclosed |
| US-20160257678-A1 | NOVEL COMPOSITIONS, USES AND METHODS FOR MAKING THEM | UNITED STATES GOVERNMENT | 2016-09-08 | — | — | US | disclosed |
| WO-2015172123-A1 | NOVEL COMPOSITIONS, USES AND METHODS FOR MAKING THEM | HADDACH MUSTAPHA (US) | 2015-11-12 | — | — | WO | disclosed |
| US-5741804-A | Substituted benzimazoles which inhibit platelet aggrecation | SMITHKLINE BEECHAM CORPORATION (US) | 1998-04-21 | — | — | US | disclosed |
| EP-0672034-A4 | BENZIMIDAZOLE COMPOUNDS WHICH INHIBIT PLATELET AGGREGATION. | SMITHKLINE BEECHAM CORP (US) | 1996-09-25 | — | — | EP | disclosed |
| EP-0672034-A1 | BENZIMIDAZOLE COMPOUNDS WHICH INHIBIT PLATELET AGGREGATION | SMITHKLINE BEECHAM CORPORATION (US) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994012478-A1 | BENZIMIDAZOLE COMPOUNDS WHICH INHIBIT PLATELET AGGREGATION | SMITHKLINE BEECHAM CORPORATION (US) | 1994-06-09 | — | — | WO | disclosed |
| US-5266320-A | Photostability, heat resistance | BASF AKTIENGESELLSCHAFT (DE) | 1993-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11618752-B2 | Compositions, uses and methods for making them | BAX, CASP3, BCL2 | PKM 3116/4885KMT2A 4232/4885AKR1B1 1948/4885 |
| US-20160326176-A1 | Novel Compositions, Uses and Methods for Making Them | BAX, CASP3, BCL2 | PKM 3075/4885KMT2A 4568/4885AKR1B1 2056/4885 |
| US-10590134-B2 | Compositions, uses and methods for making them | BAX, CASP3, BCL2 | PKM 3116/4885KMT2A 4232/4885AKR1B1 1948/4885 |
| US-10745403-B2 | Compositions, uses and methods for making them | BAX, CASP3, BCL2 | PKM 3116/4885KMT2A 4232/4885AKR1B1 1948/4885 |
| US-20200361937-A1 | NOVEL COMPOSITIONS, USES AND METHODS FOR MAKING THEM | BAX, CASP3, BCL2 | PKM 3075/4885KMT2A 4568/4885AKR1B1 2056/4885 |
| US-20160257678-A1 | NOVEL COMPOSITIONS, USES AND METHODS FOR MAKING THEM | BAX, CASP3, BCL2 | PKM 3075/4885KMT2A 4568/4885AKR1B1 2056/4885 |
| US-20210094952-A1 | NOVEL COMPOSITIONS, USES AND METHODS FOR MAKING THEM | BAX, CASP3, BCL2 | PKM 3075/4885KMT2A 4568/4885AKR1B1 2056/4885 |
| US-10442801-B2 | Compositions, uses and methods for making them | BAX, CASP3, BCL2 | PKM 3116/4885KMT2A 4232/4885AKR1B1 1948/4885 |
| US-11623928-B2 | Compositions, uses and methods for making them | BAX, CASP3, BCL2 | PKM 3116/4885KMT2A 4232/4885AKR1B1 1948/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.