Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 3/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | IARS1 | P41252 | 1/20 | 0.32 |
| ▸ | MARS1 | P56192 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL735342 | 0.90 | RNMT (0.31) | PRMT5WDR77ADORA1ADORA3 | |
| SCHEMBL735544 | 0.85 | ADORA3 (0.39) | PRMT5WDR77ADORA1ADORA3 | |
| SCHEMBL733927 | 0.82 | P2RY6 (0.37) | — | |
| SCHEMBL736839 | 0.79 | PRMT5 (0.31) | PRMT5WDR77 | |
| SCHEMBL733413 | 0.75 | — | — | |
| SCHEMBL733591 | 0.73 | P2RY6 (0.34) | — | |
| SCHEMBL7061902 | 0.69 | ADORA2A (0.43) | ADORA1ADORA3 | |
| SCHEMBL9354230 | 0.66 | MEN1 (0.38) | PRMT5WDR77ADORA1ADORA3 | |
| SCHEMBL735543 | 0.63 | TYMP (0.64) | PRMT5WDR77ADORA1ADORA3 | |
| SCHEMBL2483149 | 0.62 | P2RY12 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138330-B2 | Solid phase synthesis via deblocking immobilized nucleoside, then coupling acyl protected nucleoside phosphoramidite | SIGMA-ALDRICH CO. LLC (US) | 2012-03-20 | — | — | US | disclosed |