Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTSR1 | P30989 | 1/20 | 0.52 |
| ▸ | RORC | P51449 | 9/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7357276 | 0.82 | KRAS (0.52) | RORCKDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL20941549 | 0.74 | SAE1 (0.54) | KDM4EALDH1A1TSHRHTTPOLB | |
| SCHEMBL8248060 | 0.73 | NTSR1 (0.55) | NTSR1 | |
| SCHEMBL3465527 | 0.72 | KMT2A (0.55) | KDM4EALDH1A1TSHRHSD17B10HPGD | |
| SCHEMBL7358689 | 0.72 | NTSR1 (0.67) | NTSR1RORCALDH1A1HTT | |
| SCHEMBL13139586 | 0.72 | NTSR1 (0.57) | NTSR1KDM4EALDH1A1MAPT | |
| SCHEMBL7362873 | 0.72 | RORC (0.44) | RORCTSHRHSD17B10 | |
| SCHEMBL14876504 | 0.71 | NTSR1 (0.57) | NTSR1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL5161966 | 0.71 | IDO1 (0.48) | RORCKDM4EALDH1A1TSHRHTT | |
| SCHEMBL8029435 | 0.71 | ATM (0.53) | RORCKDM4EALDH1A1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999028297-A1 | SUBSTITUTED INDOLES, HAVING A THROMBIN INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-06-10 | — | — | WO | disclosed |